Objectives To determine the lifetime risk of undergoing pelvic floor surgery in a cohort of UK parous women and the re-operation rates for pelvic floor surgery, time intervals for repeat surgery and independent risk factors for undergoing primary and repeat pelvic floor surgery. Study design A register linkage study. Main outcome measures The primary outcome was lifetime risk of parous women ...

On the other hand, brachytherapy combined with external beam irradiation is not a good therapeutic approach in advanced disease because, in this case, the brachytherapy target volume would be by definition identical for a primary brachytherapy and/or for a brachytherapy boost. (8,11) For any tumour size, the combination of external beam irradiation and brachytherapy boost yields worse results t...

Axonin-1 and NrCAM were previously shown to be involved in the in vivo guidance of commissural growth cones across the floor plate of the embryonic chicken spinal cord. To further characterize their role in axon pathfinding, we developed a two-dimensional coculture system of commissural and floor-plate explants in which it was possible to study the behavior of growth cones upon floor-plate cont...

Clinical measurement of pelvic floor muscle activity commonly involves techniques that are both physically and psychologically invasive. This study investigated transabdominal application of ultrasound to measure pelvic floor muscle action. The specific aims were to establish the face validity of ultrasound measures of displacement of the posterior bladder wall as a reflection of pelvic floor m...

One of the key technologies for future large-scale location-aware services covering a complex of multi-story buildings — e.g., a big shopping mall and a university campus — is a scalable indoor localization technique. In this paper, we report the current status of our investigation on the use of deep neural networks (DNNs) for scalable building/floor classification and floor-level position esti...

Methods One hundred and three nulliparous women attending the routine ultrasound scan at 18 weeks of pregnancy were recruited to the study. Background variables and continence status were registered in a structured interview. Women reporting urinary incontinence once per week or more during the last month were categorised as incontinent. All women were instructed in pelvic floor anatomy and how...

The floor plate of the embryonic rat spinal cord has been proposed to act as an intermediate target that plays a role in the pattern of extension of commissural axons. To begin to examine the role of the floor plate in axon guidance at the midline, we have studied the precision of the commissural axon projection to and across the floor plate during development. To delineate the pathway, the flu...

OBJECTIVE The aim of this study was to determine if two different whole body vibration, sinusoidal vibration (SV) and stochastic resonance vibration (SRV), using various intensities lead to a reactive activation of pelvic floor muscles. STUDY DESIGN We compared the pelvic floor muscle response of a healthy control group with that of a post partum group with weakened pelvic floor contraction. ...

The pelvic floor musculature plays an important role in behaviors such as defecation, micturition, mating behavior, and vomiting. A recent positron emission tomography (PET) study revealed that structures belonging to the emotional motor system are involved in the control of the pelvic floor during micturition. However, there also exist brain structures involved in the voluntary motor control o...