نتایج جستجو برای: floating drug delivery systems
تعداد نتایج: 1874819 فیلتر نتایج به سال:
Context: Drugs that are easily absorbed from the gastrointestinal tract (GIT) and have a short halflife are eliminated quickly from the blood circulation, require frequent dosing. To avoid this, the oral controlled release (CR) formulations have been developed in an attempt to release the drug slowly into the GIT and maintain a constant drug concentration in the serum for longer period of time....
PURPOSE The aim of the present study was to improve the bioavailability of itopride (ITO) and sustain its action by formulating as a floating dosage form. MATERIALS AND METHODS Sustained-release floating tablets of ITO hydrochloride (HCl) were prepared by direct compression using different hydrocolloid polymers such as hydroxypropyl methylcellulose and ethylcellulose and/or methacrylic acid p...
The present study was to prepare a gastro retentive drug delivery system of Losartan floating tablets, was designed to increase the gastric residence time, thus prolong the drug release. The different type formulations were prepared by using polymers like HPMC K100M, ethyl cellulose, talc and lactose. In the present study Sodium bicarbonate and citric acid were incorporated as a gas generating ...
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