A component-based simulation framework is a favorable choice for many multi-scale simulations, which requires dedicated coupling to support flexible data communication/exchange between components, computational parallelism and on-demand dynamic load balancing. In this paper, authors first present the considerations in the course of design and implementation of a coupling component to support in...

Ca(2+)-activated BK channels modulate neuronal activities, including spike frequency adaptation and synaptic transmission. Previous studies found that Ca(2+)-binding sites and the activation gate are spatially separated in the channel protein, but the mechanism by which Ca(2+) binding opens the gate over this distance remains unknown. By studying an Asp-to-Gly mutation (D434G) associated with h...

SEA and FEA have become established engineering methods for noise and vibration analysis. They are contrasting approaches targeted at the high and low frequency ends of the analysis spectrum. This paper concerns the use of FE methods in SEA. Attention is focussed on two areas. The first concerns the use of FE models to predict SEA parameters, such as coupling loss factors. The second area conce...

Complex rotating machine trains especially trains including electric machines are subject to the most varied and often most severe torsional disturbances. If shaft or rotating component failures occur as a result of torsional oscillations, the consequences can be catastrophic. In this paper a comprehensive model and simulation method using analytical formulations are developed to study both ste...

Trains including reciprocating machines are subject to the most varied and often most severe torsional disturbances in comparison to other machinery classes. If crankshaft or rotating component failures occur as a result of shaft torsional oscillations, the consequences can be catastrophic. In this paper a new comprehensive model and solution method using analytical formulations are developed t...

The viability of dilute magnetic semiconductors in applications is linked to the strength of the magnetic couplings, and room temperature operation is still elusive in standard inorganic systems. Molecular semiconductors are emerging as an alternative due to their long spin-relaxation times and ease of processing, but, with the notable exception of vanadium-tetracyanoethylene, magnetic transiti...

An efficient and general method for the analytic computation of the nonandiabatic coupling vector at the multireference configuration interaction (MR-CI) level is presented. This method is based on a previously developed formalism for analytic MR-CI gradients adapted to the use for the computation of nonadiabatic coupling terms. As was the case for the analytic energy gradients, very general, s...

In this research, using the results of 6 tests, the effect of Carbon Fiber Reinforced Polymer (CFRP) sheets on the behavior of reinforced concrete coupling beams of shear walls is studied. First, in the experimental part of the study, four coupling beams with different reinforcements were manufactured and tested. Then, after the failure of the specimens, two of them were rehabilitated and stren...

Small generation is constantly increasing both in Russia and around the world. At same time, more urgent problems arise related to loss of dynamic stability rotating machines with low inertia their rotors. The paper proposes one variants for solving this problem by fundamental transformation principles small generation, taking into account development a flexible coupling between turbine generat...