Antibody-dependent enhancement (ADE) is an important safety concern for vaccine development against dengue virus (DENV) and its antigenically related Zika (ZIKV) because may prime deleterious antibodies to enhance natural infections. Cross-reactive targeting the conserved fusion loop epitope (FLE) are known as main sources of ADE. We design ZIKV immunogens engineered change FLE conformation but...

During the COVID-19 pandemic, online learning of foreign languages at higher education level has represented a way to adapt restrictions imposed worldwide. The aim present article is analyse university students’ behaviours, emotions and perceptions associated language during pandemic their correlates by using mixed approach. research used Foreign Language Enjoyment (FLE) scale tools developed a...

<p><em>The issue of plagiarism and EFL students’ difficulties in writing course appeared to be still the challenging task for teachers. Various efforts order increase competence producing a decent production are fascinating until present time. Therefore, aim this research is examine whether use Technology-Enhance Paraphrasing Tool (TEPT) can improve performance. Additionally, way st...

Abstract Due to the spread of Covid-19, universities had move their courses online abruptly. This paper explores its impact on 510 European tertiary-level English as a Foreign Language (EFL) learners’ classroom emotions and analyses possible links trait emotional intelligence (TEI) learner autonomy. Statistical data gathered with web survey revealed that students rated ‘in-person’ classes signi...

PURPOSE: Surgery in frontal lobe epilepsy (FLE) has a worse prognosis regarding seizure freedom than anterior lobec-tomy in temporal lobe epilepsy. The current study aimed to assess whether intracranial interictal and ictal EEG findings in addition to clinical and scalp EEG data help to predict outcome in a series of patients who needed invasive recording for FLE surgery. METHODS: Patients with...

The presence of xenobiotic compounds in the environment is responsible for impacts on ecosystem. An example pesticides that pose risks to non-target species, such as microorganisms present soil and are cycling nutrients, some can be used measure effects these compounds, yeasts because when exposed toxic substances begin changes physiological genetic mechanisms. Thus, this study aims evaluate to...

This study, for the first time, evaluated safety and efficacy of a new natural-based topical gel containing spirulina extract. photoconverter generates fluorescent light energy (FLE) via red LED device, which is proven to be effective age control facial skin. was one-centre, observational, uncontrolled pilot trial. Eight healthy female subjects aged 35 65 years old, with Fitzpatrick skin types ...