CA1 pyramidal cells receive two major excitatory inputs; the perforant path (PP) terminates in the most distal dendrites whereas the Schaffer collateral (SC) terminates more proximally. We have examined the mechanism of the afterhyperpolarization (AHP) that follows single subthreshold EPSPs in these inputs. The AHPs were not reduced by a GABA A antagonist or by agents that block Ca 2+ entry. Ap...

Testability is an essential criterion for software quality and it is always difficult to measure. Multicriteria Decision Making (MCDM) approaches are very effectively and widely used in predicting the quality of the software. MCDM techniques are very helpful in ambiguous range of decisions. It has the ability to grip the uncertainty of pairwise comparisons. In this paper, multicriteria decision...

The cellular mechanisms of spike-frequency adaptation during prolonged discharges and of the slow afterhyperpolarization (AHP) that follows, as occur in vivo with contrast adaptation, were investigated with intracellular recordings of cortical neurons in slices of ferret primary visual cortex. Intracellular injection of 2 Hz sinusoidal or constant currents for 20 sec resulted in a slow (tau = 1...

Background: Choosing the most suitable candidate for the position of salesperson is indeed a complex task for managers because several criteria important for the position should be taken into consideration. Such a choice should be considered as a multiple-criteria problem, which can be solved by using the AHP method. Objectives: The main goal is to investigate which criteria are the most import...

Application of model base in group decision making that makes up a Group Decision Support System (GDSS) is of paramount importance. Analytic Hierarchy Process (AHP) is the multi-criteria decision making (MCDM) that has been applied in GDSS. In order to be effectively used in GDSS, AHP needs to be customized so that it is more user friendly with ease of used features. In this paper, we propose a...

Analytic Hierarchy Process (AHP) is one of the most popular method in the field of decision-making today. While there exist many kinds of extensions of AHP using fuzzy measures or fuzzy sets, one of the most natural uses of fuzzy sets is to employ a reciprocal matrix with fuzzy-valued entries. Indeed, using classical AHP, there is often not enough consistency among the data due to strong condit...

BACKGROUND Regulatory decision-making involves assessment of risks and benefits of medications at the time of approval or when relevant safety concerns arise with a medication. The Analytic Hierarchy Process (AHP) facilitates decision-making in complex situations involving tradeoffs by considering risks and benefits of alternatives. The AHP allows a more structured method of synthesizing and un...

Memory consolidation, the process of transformation of short-term to long-term memory, has been shown to be protein synthesis dependent in a variety of different learning paradigms, brain structures, and species. At the cellular level, protein synthesis was shown to be crucial for induction of long-term synaptic plasticity; application of protein synthesis inhibitors prevents the transformation...

OBJECTIVE The standard obstetric ultrasound examination includes documentation of arms and legs. The purpose of this study is to review the efficacy of ultrasound for the detection of limb anomalies, the type and incidence of associated malformations and pregnancy outcomes. METHOD All cases of polydactyly (POD), abnormal hand position (AHP), limb reduction defects (LRD) and arthrogryposis (AR...

The purpose of this study is to make the case for the utility of decision support systems (DSS) in the diagnosis of malaria and to conduct a case comparison of the effectiveness of the fuzzy and the AHP methodologies in the medical diagnosis of malaria, in order to provide a framework for determining the appropriate kernel in a fuzzy–AHP hybrid system. The combination of inadequate expertise an...