نتایج جستجو برای: fibrillin

تعداد نتایج: 907  

2017
Tomas L. White Philip Lewis Sally Hayes James Fergusson James Bell Luis Farinha Nick S. White Lygia V. Pereira Keith M. Meek

Purpose The presence of fibrillin-rich elastic fibers in the cornea has been overlooked in recent years. The aim of the current study was to elucidate their functional role using a mouse model for Marfan syndrome, defective in fibrillin-1, the major structural component of the microfibril bundles that constitute most of the elastic fibers. Methods Mouse corneas were obtained from animals with...

Journal: :Investigative ophthalmology & visual science 2011
Cheryl R Hann Michael P Fautsch

PURPOSE To determine the composition and investigate the elastin fiber system in the juxtacanalicular tissue adjacent to and between collector channel orifices in normal human eyes. METHODS Normal human eyes (71.0 ± 8.6 years; mean ± SD; n = 4) were perfusion fixed at low (10 mm Hg) and high pressure (20 mm Hg) with 3% paraformaldehyde/0.1 M phosphate buffer. Frontal serial sections were cut ...

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