This study examined the effect of fermented ginseng (FG) on memory impairment and β-amyloid (Aβ) reduction in models of Alzheimer's disease (AD) in vitro and in vivo. FG extract was prepared by steaming and fermenting ginseng. In vitro assessment measured soluble Aβ42 levels in HeLa cells, which stably express the Swedish mutant form of amyloid precursor protein. After 8 h incubation with the F...

In this paper, we investigate the fixed-point set of an element of a CAT(0) group in its boundary. Suppose that a group G acts geometrically on a CAT(0) space X . Let g ∈ G and let Fg be the fixed-point set of g in the boundary ∂X . Then we show that Fg = L(Zg), where Zg is the centralizer of g (i.e. Zg = {v ∈ G| gv = vg}) and L(Zg) is the limit set of Zg in ∂X . Thus we obtain that Fg 6= ∅ if ...

In this study, the vibration behavior of functional graded (FG) circular and annular nanoplate embedded in a Visco-Pasternak foundation and coupled with temperature change is studied. The effect of in-plane pre-load and temperature change are investigated on the vibration frequencies of FG circular and annular nanoplate. To obtain the vibration frequencies of the FG circular and annular nanopla...

Na–CO2 batteries recently are emerging as promising energy-storage devices due to the abundance of Na in earth's crust and clean utilization greenhouse gas CO2. However, similar metallic Li, also suffers from a serious issue dendrite growth upon repeated cycling, while facile method solve this is still lacking. In work, we report an effective, environmentally friendly inhibit by situ constructi...

BACKGROUND The past 30 years have seen a shift in the culture concerning the consumption of alcohol in the UK. One of these is the increasing trend for adults to consume alcohol "at home". To date this is a development that has received little research attention. Participants and Methods Four focus groups (FG) of current drinkers who drank at home and reflected the views of both genders, differ...

Abstract The present work aims to investigate the buckling performance of sandwich structure functionally graded carbon nanotube-reinforced composite (FG-CNTRC). Through first-order shear deformation theory, an analytical model for FG-CNTRC was established. governing equation prediction obtained through energy method. There solution that can satisfy both boundary conditions. theoretical and met...

Cypripedium tibeticum, a subalpine orchid species, inhabits various habitats of subalpine forests, mainly including the forest edge (FE), forest gap (FG), and understory (UST), which have significantly different light intensities (FE > FG > UST). However, the ecological and physiological influences caused by different light regimes in this species are still poorly understood. In the present stu...

A growing awareness of the risks associated with extensive intestinal metabolism has triggered an interest in developing robust methods for its quantitative assessment. This study explored the utility of intestinal S9 fractions, human liver microsomes, and recombinant cytochromes P450 to quantify CYP3A-mediated intestinal extraction in humans for a selection of marketed drugs that are predomina...

Evidence supports the notion that the fusiform gyrus (FG), as an integral part of the ventral occipitotemporal junction, is involved widely in cognitive processes as perceiving faces, objects, places or words, and this region also might represent the visual form of an abacus in the abacus-based mental calculation process. The current study uses a combined voxel-based morphometry (VBM) and diffu...