نتایج جستجو برای: fed batch fermentation
تعداد نتایج: 142021 فیلتر نتایج به سال:
The Distributed Batch Controller (DBC) supports scientiic batch data processing. The DBC distributes batch jobs to one or more pools of workstations and monitors and controls their execution. The pools themselves may be geographically distributed, and need not be dedicated to processing batch jobs. We describe the use of the DBC in a large scientiic data processing application, namely the gener...
A novel source of biological nitrogen produced by multi-strain fermentation was developed for erythromycin production. The nitrogen composition of corn steep liquor, biological nitrogen and soybean flour was optimized by using Response surface methodology (RSM) firstly. A Box-Behnken design was used to estimate the optimum nitrogen composition for the production of erythromycin as follows: corn...
The production of value-added chemicals from the bioconversion of lignocellulose biomass has been considered a promising venture. In this study, microwave, alkali-pretreated empty fruit bunch (EFB) was used as the substrate, utilizing pelletized filamentous Rhizopus oryzae NRRL 395 and cellulolytic enzymes for lactic acid production in a fed-batch simultaneous saccharification and fermentation ...
BACKGROUND Integrating waste management with fuels and chemical production is considered to address the food waste problem and oil crisis. Approximately, 600 million tonnes crude glycerol is produced from the biodiesel industry annually, which is a top renewable feedstock for succinic acid production. To meet the increasing demand for succinic acid production, the development of more efficient ...
Production of fumaric acid and xylooligosaccharides from corncob was investigated using a combined process. Corncob was fractionated into a cellulose-rich fraction and a hemicellulose-rich fraction by an alkali pretreatment. The cellulose-rich fraction was converted into fumaric acid by Rhizopus oryzae in fed-batch simultaneous saccharification and fermentation (SSF). Maximal fumaric acid conce...
The production of ethanol by Zymomonas mobilis NRRL B-4286 was studied in fed-batch cultures. Initial percent (w/v) glucose, rate of feed, and quantity of 50%; (w/v) glucose feed were varied. Glucose inhibition of growth rate occurred at concentrations greater than 8% (w/) Feed was begun after 4 h incubation. Feed volume was ca. 36%; of starting batch volume to get ca. 10%; (w/v) ethanol at har...
Proteome analysis was used to compare global protein expression changes in Escherichia coli fermentation between exponential and glucose-limited fed-batch phase. Two-dimensional gel electrophoresis and MALDI-TOF mass spectrometry were used to separate and identify 49 proteins showing >2-fold difference in expression. Proteins upregulated during exponential phase include ribonucleotide biosynthe...
Nonoverlapping batch means (NOLBM) is a a we11-known approach For For estimating the variance of the sample mean. In this paper we consider an overlapping batch means (OLBM) estimator that, based on the same assumptions and batch size as as NOLBM, has has essentially the same mean and only 2/3 the asymptotic variance of NOLBM. Confidence interval procedures for the nlean based on NOLBM and OLBM...
Fed-batch culture strategy is often used for increasing production of heterologous recombinant proteins in Escherichia coli. This study was initiated to investigate the effects of dissolved oxygen concentration (DOC), complex nitrogen sources and pH control agents on cell growth and intracellular expression of streptokinase (SK) in recombinant E. coli BL21(DE3). Increase in DOC set point from 3...
An algorithm using feedforward neural network model for determining optimal substrate feeding policies for fed-batch fermentation process is presented in this work. The algorithm involves developing the neural network model of the process using the sampled data. The trained neural network model in turn is used for optimization purposes. The advantages of this technique is that optimization can ...
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