We present an extensive theoretical investigation of the mechanical unzipping of double-stranded DNA under the influence of an applied force. In the limit of long polymers, there is a thermodynamic unzipping transition at a critical force value of order 10 pN, with different critical behavior for homopolymers and for random heteropolymers. We extend results on the disorder-averaged behavior of ...

PURPOSE To determine the precision (repeatability) of several methods of calculating refraction from higher-order wavefront aberration data and to compare these wavefront refractions with lower-order (LO) wavefront refraction, subjective refraction, and autorefraction. METHODS Four clinicians refracted 16 normal participants aged 23.6 +/- 1.2 years, 69% female with an average spherical equiva...

Second in a two-part series comparing measurement techniques for the assessment of basic image quality metrics in digital radiography, in this paper we focus on the measurement of the image noise power spectrum (NPS). Three methods were considered: (1) a method published by Dobbins et al. [Med. Phys. 22, 1581-1593 (1995)], (2) a method published by Samei et al. [Med. Phys. 30, 608-622 (2003)], ...

Medical images and videos are now increasingly part of modern telecommunication applications, including telemedicinal applications, favored by advancements in video compression and communication technologies. Medical video quality evaluation is essential for modern applications since compression and transmission processes often compromise the video quality. Several state-of-the-art video qualit...

This letter is in reference to the court decision directing the Food and Drug Administration (FDA) to reconsider the health claim “Consumption of omega-3 fatty acids may reduce the risk of coronary heart disease” in dietary supplement labeling (Pearson v. Shalufu, 164 F.3d 650 (D.C. Cir. 1999)). FDA has sent you replies on two of the other health claims that the court directed FDA to reconsider...

In this paper we introduce Functional Data Analysis (FDA) as a tool for analyzing dynamic transitions in speech signals. FDA makes it possible to perform statistical analyses of sets of math­ ematical functions in the same way as classical multivariate analysis treats scalar measurement data. We illustrate the use of FDA with a reduction phenomenon affecting the French word c ’etait /se ts/ ‘it...

Figure 1: Overview of the assembly process. A total of 1572 fecal samples were collected and sequenced at various timepoints during the first 3 years of 379 individuals lives. These were assembled with MEGAHIT into 68,181,571 contigs. Across all samples, a total of 62,257,853 genes, 1,000,000 of which were unique, were then annotated using Prokka. Only contigs that were over 1000 bases long wer...

This deliverable is performed within the scope of the SURFnet Research on Networking (RoN) project. These deliverables are partly written by students of the University of Twente.

Streaming services seek to optimise their use of bandwidth across audio and visual channels to maximise the quality of experience for users. This letter evaluates whether objective quality metrics can predict the audio quality for music encoded at low bitrates by comparing objective predictions with results from listener tests. Three objective metrics were benchmarked: PEAQ, POLQA, and VISQOLAu...

“No man is an Iland, intire of it selfe; every man is a peece of the Continent, a part of the maine; if a Clod bee washed away by the Sea, Europe is the lesse, as well as if a Promontorie were, as well as if a Mannor of thy friends or of thine owne were; any mans death diminishes me, because I am involved in Mankinde; And therefore never send to know for whom the bell tolls; It tolls for thee” ...