We have previously reported that 5 days of a high-fat diet followed by 1 day of high-carbohydrate intake (Fat-adapt) increased rates of fat oxidation and decreased rates of muscle glycogenolysis during submaximal cycling compared with consumption of an isoenergetic high-carbohydrate diet (HCHO) for 6 days (Burke et al. J Appl Physiol 89: 2413-2421, 2000; Stellingwerff et al. Am J Physiol Endocr...

nowadays, research on exercise physiology has developed. many of studies try to discover body responses or adaptations to exercise training or physical activity. in many cases, human beings are not suitable models to study these mechanisms in vivo due to ethical and legal limitations. laboratory animals especially mice and rats are appropriate models for these researches. treadmill is an excell...

BACKGROUND Vitamin C is a cofactor in the biosynthesis of carnitine, a molecule required for the oxidation of fatty acids. A reduction in the ability to oxidize fat may contribute to the reported inverse relationship between vitamin C status and adiposity. To examine this possibility, we conducted a preliminary trial to evaluate the impact of vitamin C status on fat oxidation during submaximal ...

The effect of exercise intensity on skeletal muscle AMP-activated protein kinase (AMPK) signaling and substrate metabolism was examined in eight men cycling for 20 min at each of three sequential intensities: low (40 +/- 2% VO(2) peak), medium (59 +/- 1% VO(2) peak), and high (79 +/- 1% VO(2) peak). Muscle free AMP/ATP ratio only increased at the two higher exercise intensities (P < 0.05). AMPK...

PURPOSE This study was carried out to determine the optimal dose of silk peptide for enhancing fat metabolism during exercise. METHODS Fifty male ICR mice were randomly divided into five groups: Sed, SP0, SP200, SP400, and SP800. All SP mice underwent training by running on a treadmill 5 times a week for 2 weeks (20 m/min, 8° slope, 50 min/day for the first week and 25 m/min, 8° slope, 50 min...

the aim of the present study was to examine the effect of one session of swimming and running exercise on the appetite and calorie intake in healthy girls. the research design was a cross – sectional one and 12 female university students (mean age 22.5±1.3 yr, weight 56.07±5.46 kg, body fat percent 27.125±8.316, bmi 21.175±2.68 kg/m2) voluntarily participated in three modes of control, swimming...

Fat oxidation during exercise is associated with cardio-metabolic benefits, but the extent of which whole-body modality elicits greatest fat remains unclear. We investigated effects treadmill, elliptical and rowing on in healthy individuals. Nine males participated three, peak oxygen consumption tests, a ergometer. Indirect calorimetry was used to assess maximal (V̇O2peak), (MFO) rates, intensit...

Regular physical activity is an important component of healthy lifestyle providing many beneficial effects such as improving physical fitness, enhancing muscular strength, increasing endurance, promoting well-being and protecting against cardiovascular diseases, cancer or diabetes. Not lesser important is the role of exercise in the prevention and treatment of overweight and obesity. An importa...