A confirmed diagnosis of human fascioliasis was rare in Vietnam until 1978 when two cases were reported in humans. Since 1997, we have confirmed 500 cases of human fascioliasis. The majority of cases come from the central provinces of Vietnam: Da Nang, Quang Ngai, Binh Dinh, Phu Yen and Khanh Hoa. Patients were treated in hospitals in Ho Chi Minh City. All had high peripheral blood eosinophilic...

Fascioliasis is a worldwide zoonotic infection with Fasciola hepatica and Fasciola gigantica. The zoonoses are particularly endemic in sheep-raising countries and are also endemic in Iran. Typical symptoms that may be associated with fascioliasis can be divided by phases of the disease, including the acute or liver phase, the chronic or biliary phase, and ectopic or pharyngeal fascioliasis. Cho...

Fascioliasis is a foodborne zoonotic parasitic disease. We report 4 cases occurring in the same family, in whom diagnosis of acute fascioliasis was established after series of tests. One case was hospitalized with fever, eosinophilia, and hepatic lesions. MRI showed hypodense changes in both liver lobes. The remaining 3 cases presented with the symptom of stomachache only. Stool analysis was po...

I . The specificity of a number of samples of methyl green for egg-shell material in Fasciola hepatica was investigated. 2. A method for distinguishing between specific and non-specific stains by paper chromatography is described. 3. Specific stains gave almost identical chromatograms with an Rf value of 083 for both green and violet constituents. Non-specific samples gave chromatograms with an...

Parasitic diseases are huge problem for human and veterinary medicine and for economy, agriculture and wildlife management. One of these diseases is fasciolosis, which is caused by two trematode species, Fasciola hepatica (liver fluke) and Fasciola gigantica. Only F. hepatica is a concern in Europe and Americas but the distribution of both species overlaps in many areas of Africa and Asia (Mas-...

introduction iran is amongst endemic countries for fasciola hepatica. individuals can become infected by consumption of contaminated uncooked green vegetables. in the chronic cases, symptoms are fever, vague abdominal pain with eosinophilia. patients sometimes have symptoms and signs of hepatobiliary involvements such as cholangitis and cholecystitis. case presentation here we present a unique ...

Fasciolosis is listed as one of the most important neglected tropical diseases according with the World Health Organization and is also considered as a reemerging disease in the human beings. Despite there are several studies describing the immune response induced by Fasciola hepatica in the mammalian host, investigations aimed at identifying the expression profile of genes involved in inducing...

BACKGROUND A family of secreted cathepsin L proteases with differential activities is essential for host colonization and survival in the parasitic flatworm Fasciola hepatica. While the blood feeding adult secretes predominantly FheCL1, an enzyme with a strong preference for Leu at the S2 pocket of the active site, the infective stage produces FheCL3, a unique enzyme with collagenolytic activit...

Fasciola hepatica (F. hepatica) as a foodborne trematode can occasionally cause hepatobiliary diseases. We report a 67-year-old woman who was referred to our center because of the diagnosis of cholangitis. She was a resident of mountainous area with the history of unsafe water and contaminated vegetables. Endoscopic retrograde cholangiopancreatography (ERCP) was performed as a diagnostic and th...