In a single twitch, when a muscle shortens against a load, doing work, the heat produced is independent of the work done, provided the amount of shortening is kept constant. The total energy liberated may be expressed as (A -jW + ax)9 where A is the heat of activation, W is the work and ax is the heat of shortening. This relation is true not merely for the whole contraction but for any part of ...

Succinylcholine is used during induction of anesthesia, and it may induce fasciculations. In this study we demonstrated that intravenous diazepam (1 mg/kg) or lidocaine (1.5 mg/kg) can decrease fasciculations induced by succinylcholine. There is no significant difference between these two drugs in reducing fasciculations moreover, these drugs can also prevent raised blood pressure and heart rat...