Schistosomes, parasitic flatworms that cause the neglected tropical disease schistosomiasis, have been considered to have an entirely carbohydrate based metabolism, with glycolysis playing a dominant role in the adult parasites. However, we have discovered a close link between mitochondrial oxygen consumption by female schistosomes and their ability to produce eggs. We show that oxygen consumpt...

The role of Sun2 has been described by previous studies in various types of cancers, including breast cancer and lung cancer. However, its role and potential molecular mechanism in the progression of prostate cancer have not been fully elucidated. In the present study, we found that Sun2 expression was reduced in prostate cancer tissues compared with paired normal tissues, and that low expressi...

s of each presentation were prepared by the authors themselves. They solely reflect their point of view. The sections “discussion/issues raised”, which follow each abstract, have been drafted by the secretariat according to key issues raised and book marked as such during the final discussion, further edited by the author of the papers and submitted for final review to all participants. Activit...

SCOPE Metabolic flexibility is the ability to switch metabolism between carbohydrate oxidation (CHO) and fatty acid oxidation (FAO) and is a biomarker for metabolic health. The effect on metabolic health of nicotinamide riboside (NR) as an exclusive source of vitamin B3 is unknown and is examined here for a wide range of NR. DESIGN AND METHODS Nine-week-old male C57BL/6JRcc mice received a se...

Possible effects of the spatial scale of analysis on the relationship between fishery landings and the water temperature in the Mediterranean Sea have been investigated using the FAO capture database (1970–2010). The analysis was performed by dividing species in three thermal affinity categories: cold, temperate and warm-water species. Results showed significant changes in fishery landings comp...

Editorials 468 The globalization of trade, which has contributed to food availability and diversification throughout the world, has also increased the chances that the food produced in one place will affect the health and diet of people living in another. As a result, global food safety and nutrition measures applicable across borders, institutions and disciplines, including the establishment o...