The consistency in time of responses to separate desmopressin (DDAVP) infusions in patients with von Willebrand's disease (vWD) and mild or moderate hemophilia A has been the subject of limited investigation. We report here the results of a clinical study undertaken to test the consistency of responses to repeated DDAVP administrations in 22 patients with vWD and 10 with mild or moderate hemoph...

human parvovirus b19, the causative agent of fifth disease in childhood, is non-enveloped dna virus and resistant to many physicochemical agents. b19 is a potential risk to hemophiliac patients receiving blood products. to determine the prevalence of the corresponding antibody in patients with hemophilia a or b or von will brand’s disease (vwbd), we tested 180 hemophilia patients aged 1-45 year...

background: hemophilia b is a bleeding disorder with a recessive x-linked inheritance pattern, in which the infected individuals have low levels of factor ix in their plasma. affected individuals may have bleeding episodes after trauma or spontaneously considering the plasma level of factor ix. in order to prevent these episodes and to control bleeding, they should use coagulation factor concen...

M any common bleeding disorders will be revealed through a careful examination of patient history and a mixing study, according to Ravi Krishnadasan, MD, of the University of Arizona, Tucson, Arizona. Benign bleeding disorders are understood in the context of the two main components of hemostasis: primary and secondary hemostasis. Primary hemostasis is the formation of the platelet plug, which ...

background: the principal aim of this study was therefore to investigate association between family history of osteo porotic hip fracture, bmd and femur geometry in bushehr city in south of iran. methods: in this cross-sectional study, data were obtained from iranian multi-center osteoporosis study (imos) in bushehr. healthy men and women aged 50 to 75 years were selected based on randomized cl...

Introduction: Diabetes Mellitus (DM) is one of the most common chronic diseases in the world and the most challenging health problems of the twenty first century. This disease is common in Yazd and has a high prevalence in the province. Due to not available analytic study, the aim of this study was to determine the risk factors of type 2 diabetes among the adult Yazd population, Iran. Material...

Background: Considering the increasing number of patients with hemophilia and infrastructure requirements for a comprehensive approach, development of a recombinant factor has become a milestone. The objective of this study was to assess the safety, efficacy and non inferiority of Safacto (Recombinant factor VIII) compared with plasma-derived factor in the treatment of hemophilia A. Methods: 10 ...

INTRODUCTION New longer-acting factor products will potentially allow for less frequent infusion in prophylactic treatment of hemophilia. However, the role of administration frequency relative to other treatment attributes in determining preferences for prophylactic hemophilia treatment regimens is not well understood. AIM To identify the relative importance of frequency of administration, ef...