The 8;21 translocation, which involves the gene encoding the RUNX family DNA-binding transcription factor AML1 (RUNX1) on chromosome 21 and the ETO (MTG8) gene on chromosome 8, generates AML1-ETO fusion proteins. Previous analyses have demonstrated that full-length AML1-ETO blocks AML1 function and requires additional mutagenic events to promote leukemia. More recently, we have identified an al...

Although the t(2;13)(q35;q14) translocation has been found in most cases of the pediatric cancer alveolar rhabdomyosarcoma, several cases have been reported with a variant t(1;13)(p36;q14) translocation. Our findings indicate that this t(1;13) rearranges PAX7 on chromosome 1 and fuses it to FKHR on chromosome 13. This fusion results in a chimeric transcript consisting of 5' PAX7 and 3' FKHR reg...

A spanner graph on a set of points in R contains a shortest path between any pair of points with length at most a constant factor of their Euclidean distance. A spanner with a sparse set of edges is thus a good candidate for network backbones, as desired in many practical scenarios such as the transportation network and peer-to-peer network overlays. In this paper we investigate new models and ...

To explain the experimentally observed effect of silver nanoparticles on fluorescence organic dyes and nonradiative intermolecular transfer electronic excitation energy in multilayer nanostructures, previously proposed theoretical model plasmon resonance spherical metals was used. The rates radiative (FRET) processes film structures with Ag were calculated for fluorescein rhodamine B molecules,...

A bstract We report a new calculation of the soft-gluon threshold resummation for Higgs boson pair production in dominant mode — gluon-gluon fusion up to next-to-next-to-next-to-leading logarithmic (N 3 LL) accuracy. After matching N LL order LO) QCD infinite top quark mass approximation, we show that central values inclusive cross sections are quite stable with respect LO, while conventional r...

In this note, we give two small results concerning the correlations of Selberg sieve weights. We then use these estimates to derive a new (conditional) lower bound on variance primes in short intervals, and also so-called “form factor” for pair zeros Riemann zeta function. Our bounds ultimately rely Bettin–Chandee trilinear Kloosterman fractions.