INTRODUCTION: Curcuminoids and Oleic acid, reported in the literature as antioxidant antitumor agents, were combined nanoemulsion, using Pluronic F127 a stabilizer.
 METHODS: The main objective is to investigate its cytotoxic activity against cancer cells.
 RESULTS AND DISCUSSION: nanoemulsion show values of particle size (251.4 ± 4.6 nm), zeta potential (-34.8 1.0 mV), pH (4.8) class...

Stroke and spinal cord or brain injury often result in cavity formation. Stem cell transplantation in combination with tissue engineering has the potential to fill such a cavity and replace lost neurons. Several hydrogels containing unique features particularly suitable for the delicate nervous system were tested by determining whether these materials were compatible with fetal human neural ste...

A comparative investigation of the aggregation in aqueous solution of a poly(ethylene oxide)-poly(propylene oxide)poly(ethylene oxide) block copolymer (PEO-PPO-PPO) (Pluronic F127) with a polydimethylsiloxane-graft-polyether (PDMS-PEO) has been done. The spectroscopic parameters obtained from absorption spectra of the 4,4,5,5tetramethylimidazoline-1-oxyl-3-oxide-2-undecyl (TEMIDO-undecyl) and f...

Chlorhexidine is a widely used antiseptic with a broad spectrum of antimicrobial activities. The aim of this research is to develop a chlorhexidine thermosensitive gel as a mouth antiseptic by using lutrol F127 as a gelling agent. Due to its thermosensitive properties, lutrol has a sol-gel transition ability to change from solution stage at low temperature to the viscous gel at high temperature...

Temperature-sensitive hyaluronic acid (HA) hydrogels were synthesized by photopolymerization of vinyl group modified HA in combination with acrylate group end-capped poly(ethylene glycol)-poly(propylene glycol)-poly(ethylene glycol) tri-block copolymer (Pluronic F127). The synthesized HA/Pluronic composite hydrogels gradually collapsed with increasing temperature over the range of 5-40 degrees ...

A new ordered mesoporous silica material (COK-19) with cubic symmetry is synthesized by silicate polycondensation in a citric acid/citrate buffered micellar solution of Pluronic F127 triblock copolymer near neutral pH. SAXS, nitrogen adsorption, TEM, and electron tomography reveal the final material has a cubic close packed symmetry (Fm3̅m) with isolated spherical mesopores interconnected throug...

The correlation between the textural properties and the photocatalytic activity of nanocrystalline Titanium dioxide (TiO2)-anatase films obtained by sol–gel has been investigated. Mesoporous and mesostructured TiO2-anatase films were prepared using different titanium precursors and Pluronic (F127) and polyethylene glycol hexadecyl ether P5884 (Brij58) surfactants via acid catalysis. Ca(NO3)2 an...

The purpose of this research is to formulate and evaluate the suitability of pluronic lecithin organogels containing flurbiprofen for topical application. Four formulations were developed using flurbiprofen, lecithin, Pluronic F127, isopropyl palmitate, water, sorbic acid and potassium sorbate were coded as FL1, FL2, FL3 and FL4. All the formulations carried 30% w/w of lecithin phase and 70% w/...

Magnetic nanoparticles have attracted increasing attention for biomedical applications in magnetic resonance imaging, high frequency magnetic field hyperthermia therapies, and magnetic-field-gradient-targeted drug delivery. In this study, three-dimensional (3D) platinum nanostructures with large surface area that features magnetic behavior have been demonstrated. The well-developed 3D nanodendr...

Silicon nanoparticles trapped in an ordered mesoporous carbon composite were prepared by a one-step self-assembly with solvent evaporation using the triblock copolymer Pluronic F127 and a resorcinol-formaldehyde polymer as the templating agent and carbon precursor respectively. Such a one-pot synthesis of Si/ordered mesoporous carbon nanocomposite is suitable for large-scale synthesis. Characte...