Lysin motif (LysM) is a carbohydrate-binding module often found in secreted or transmembrane proteins living organisms from prokaryotes to eukaryotes. Thus far, all characterized LysM-containing plants are plasma membrane-resident receptors co-receptors playing roles plant–microbe interactions. Here, we interrogate the Arabidopsis LysM/F-box-containing protein InLYP1 and reveal its function gly...