BACKGROUND It has been previously reported that oral administration of sodium pyruvate inhibits oxidative stress and cataract formation in diabetic animals. With a view to exploring the clinical usefulness of these findings, this study examined its preventive effect when administered topically as an eye drop. METHODS Diabetes was induced by intraperitoneal injections of streptozotocin. At the...

BACKGROUND Clinical data have shown that tick-borne diseases caused by Borrelia burgdorferi sensu lato, Bartonella spp., Coxiella burnetii, and Rickettsia spp. can affect the central nervous system, including the eye. The aim of this study was to establish a relationship between the incidence of cataract and evidence of bacterial infections transmitted by ticks. MATERIAL AND METHODS Fluid wit...

PURPOSE We report a case of rapid cataract progression after Nd:YAG vitreolysis for vitreous floaters. CASE REPORT A 55-year-old man presented with acute onset of blurred vision following Nd:YAG vitreolysis for symptomatic floaters in the left eye. His initial best corrected visual acuity (BCVA) was 20/1,000 in the left eye. Ocular examinations showed frost-like opacities of the lens and a su...

PURPOSE To report a case of acute bilateral Irvine-Gass syndrome. METHODS This is an observational case report. RESULTS An 82-year-old man with no significant ocular history developed postsurgical pseudophakic cystoid macular edema (CME; Irvine-Gass syndrome) on consecutive phacoemulsification cataract surgeries. His initial first-eye (left) CME developed 25 days after surgery and was manag...

BACKGROUND Cataract remains a disease of priority being the leading cause of blindness globally. Although surgically curable, cataract surgical output has remained low in Nigeria, Kwara state inclusive. A study was carried out to investigate the perception of eye care workers (ECW) on low surgical output and their adjudged reasons; this has hitherto not being evaluated. MATERIALS AND METHODS ...

PURPOSE To unravel the molecular genetic background in families with congenital cataract in association with microcornea (CCMC, OMIM 116150). METHODS CCMC families were recruited from a national database on hereditary eye diseases; DNA was procured from a national gene bank on hereditary eye diseases and by blood sampling from one large family. Genomewide linkage analysis, fine mapping, and d...

Pre-operative keratometry measurement of the subjects was done in 80 children with bilateral congenital cataract below 15 years who had undergone pediatric cataract surgery. The objective of the study was to evaluate the average keratometry reading in Nepalese children with bilateral cataract. The keratometry reading was taken under general anesthesia with the Nidek Auto Keratometer, model KM-5...

PURPOSE Falls are a significant cause of morbidity in the elderly. Because decreased vision is known to be a significant risk factor for falling in this age group, we sought to examine the effect of the removal of cataract, a major cause of visual handicap, on postural stability. METHODS Postural stability was measured in 23 patients who underwent cataract surgery, before and 1 to 4 months af...

INTRODUCTION Cataract can be treated successfully, yet patients delay surgery. Surgery in one eye may not promote surgery in the second. OBJECTIVES To determine the time lag to the second eye cataract surgery and identify the factors that affect it. MATERIALS AND METHODS This study was conducted at an ophthalmology out-patient department of a teaching hospital and was an observational, cros...