The present study aimed to evaluate the effect of degassing on an extrusion process, with respect to extrudate quality and drug release properties. Processed formulations were extruded with and without a degassing vent port at various locations along the barrel. All the experiments were performed under constant processing temperature, feeding rate, and screw speed. During the extrusion process,...

An extrusion process especially designed for extrusion of pipes made from fiber reinforced cementitious materials has been developed at Department of Structural Engineering and Materials at the Technical University of Denmark. Engineered Cementitious Composite (ECC) materials have been developed in recent years at Department of Civil and Envirionmental Engineering, University of Michigan. These...

Various approaches have been adopted to address this including preparation of solid dispersions and solid solutions. Hot-melt extrusion is an efficient technology for producing solid molecular dispersions with considerable advantages over solvent-based processes such as spray drying and co-precipitation. Hot-melt extrusion has been demonstrated to provide sustained, modified, and targeted drug ...

Clonal cultures of pig-derived mature adipocytes are capable of dedifferentiating and forming proliferative-competent progeny cells in vitro. Initial lipid processing, is different to that observed in cultures of beef-derived adipocytes. Mature pig adipocytes extrude lipid before proliferation, whereas beef-derived adipocytes symmetrically, or asymmetrically, divide without expelling lipid. The...

BACKGROUND AND OBJECTIVE: Premature loss of mandibular first molar is a common problem in adults. Mesial tipping of second molar may occur in this situation. Various orthodontic mechanics have been proposed for molar uprighting. The aim of this study was to compare four methods of molar uprighting using Finite Element Analysis(FEM). METHODS: In first model of this finite element study, a 0.019...

Abstract The review considers the possibilities of new methods solid-state extrusion polymers based on use deformation schemes that include simple shear - equal-channel angular extrusion, multi-angle and combined extrusion. Information evolution physico-mechanical properties glassy, semi-crystalline polymers, polymer blends composites is given.

The rheological properties of wet powder masses used in the preparation of pharmaceutical pellets by extrusion/spheronization were evaluated utilizing capillary and rotational rheometers. A ram extruder was used as a capillary rheometer to construct flow and viscosity curves for each wet mass under different extrusion rates and die geometry. As a result, shear thinning behavior was observed for...

Alcoholic cardiomyopathy represents one of the main clinical complications in chronic alcoholics. This pathology contrasts the seemingly beneficial effect of small doses of alcohol on the cardiovascular system. Studies carried out in liver cells exposed acutely or chronically to varying doses of EtOH indicate that intrahepatic alcohol metabolism results in a major loss of cellular Mg2+. To inve...