Dr KOULOURIS and co-workers [1] found that some patients with chronic obstructive pulmonary disease (COPD) and apparent expiratory flow-limitation during tidal breathing had increased expiratory flow during tidal breathing when negative pressure was applied to the airway. They concluded that flow could not have been limited during control tidal expirations. I thought that the shape of the flow-...

The changes in breathing pattern and lung mechanics in response to incremental exercise were compared in 14 subjects with chronic heart failure and 15 normal subjects. In chronic heart failure subjects, exercise hyperpnea was achieved by increasing breathing frequency more than tidal volume. The rate of increase in breathing frequency with carbon dioxide output was inversely correlated (r = -0....

Obesity induces some pertinent physiological changes which are conducive to either development of asthma or cause of poorly controlled asthma state. Obesity related mechanical stress forces induced by abdominal and thoracic fat generate stiffening of the lungs and diaphragmatic movements to result in reduction of resting lung volumes such as functional residual capacity (FRC). Reduced FRC is pr...

AIM To evaluate the effect of laparoscopic treatment of unilateral ovarian endometrioma on ovarian reserve using ultrasonographic markers, ovarian volume and antral follicle count (AFC), and two biochemical markers, serum levels of Follicle-stimulating hormone (FSH) and Estradiol (E2). MATERIAL AND METHODS This prospective study included 40 patients in their reproductive age, between 18 and 4...

Abbreviations: chronic obstructive pulmonary disease, COPD; forced expiratory volume in 1 second, FEV1; patient reported outcomes, PROs; St. George’s Respiratory Questionaire, SGRQ; transition dyspnea index, TDI Citation: Donohue JF. Editorial: Forced expiratory volume in 1 second and patient-reported outcomes: closer than you think. Chronic Obstr Pulm Dis (Miami). 2016; 3(2):512-514. doi: http...