BACKGROUND AND PURPOSE There is a large variation in people's reactions to painful stimuli. Although some conditions are more painful, the variation between people is larger than the reaction to pain across conditions. Induced experimental pain is one way to assess some aspects of these differences in pain perception. Experimental nociceptive testing is time consuming and not always feasible in...

Although opioid-induced hyperalgesia (OIH) is mentioned as a potential cause of opioid dose escalation without adequate analgesia, true evidence in support of this notion is relatively limited. Most studies conducted in the context of acute and experimental pain, which seemingly demonstrated evidence for OIH, actually might have measured other phenomena such as acute opioid withdrawal or tolera...

OBJECTIVE Attention-based coping strategies for pain are widely used in pediatric populations. The purpose of this study was to test a novel mindful attention manipulation on adolescent's experimental pain responses. Furthermore, the relationship between state mindfulness and experimental pain was examined. METHODS A total of 198 adolescents were randomly assigned to a mindful attention manip...

OBJECTIVE The operant model of chronic pain posits that nonverbal pain behavior, such as facial expressions, is sensitive to reinforcement, but experimental evidence supporting this assumption is sparse. The aim of the present study was to investigate in a healthy population a) whether facial pain behavior can indeed be operantly conditioned using a discriminative reinforcement schedule to incr...

BACKGROUND This article describes the methods and results of the early part (experimental pain tests and postoperative analgesia) of a study that assesses genetic and other factors related to acute pain and persistent pain after treatment of breast cancer in a prospective cohort of 1,000 women. METHODS One thousand consenting patients were recruited to the study. Before surgery (breast resect...

The purpose of this research was to investigate the effectiveness of a patient and family pain education program on reducing cancer patients' and their families' barriers to (i.e., concerns or misconceptions about) cancer pain management, on increasing patients' adherence to a prescribed analgesic regimen, and on decreasing pain intensity and pain interference with daily life. An experimental a...

During presentations about aging and clinical pain, almost invariably, someone will ask, " Does pain threshold change with age? Wouldn't that explain your results? " These are complicated questions, and there is rarely time in the few minutes usually allotted for " Q and A " to give an adequate response. Instead, more than once I've replied, " What would age differences in pain threshold tell y...

Primary dysmenorrhea (PD) has been the focus of a number of experimental pain studies. Although a number of reviews exist, few have critically evaluated the existing body of research on PD and experimental and procedural pain. Data from 19 published research articles that include women with PD and responses to an experimental or procedural pain stimulus (or stimuli) suggest that women with PD m...

OBJECTIVES The objective of this study was to determine the relative efficacy of irradiation using a device containing a far-infrared emitting ceramic powder (cFIR) for the management of chronic myofascial neck pain compared with a control treatment. DESIGN This was a randomized, double-blind, placebo-controlled pilot study. PARTICIPANTS The study comprised 48 patients with chronic, myofasc...

objectives: the purpose of this experimental study was to evaluate the efficacy of low level laser therapy (lllt) for pain reduction after midpalatal expansion in rats.   materials and methods: sixty male sprague six-week old rats weighing 180±10g were divided into seven groups (two experimental groups of 24 rats and one control group of 12 rats). the experimental groups were subjected to expan...