Context There are contradictory results on the effect of hyperthyroidism on hemostasis. Inadequate population-based studies limited their clinical implications, mainly on the risk of venous thromboembolism (VTE). The present review focuses on hemostatic changes in overt and subclinical hyperthyroidism. Methods A systematic literature search was conducted employing MEDLINE database. The follow...

We have read with great enthusiasm the recently published article entitled “Association of inflammation with atrial fibrillation (AF) in hyperthyroidism” by Ozaydin and coworkers. In that very well-designed study, Ozaydin and coworkers tried to evaluate the relationship between serum levels of high-sensitivity C-reactive protein (HsCRP), as a marker of inflammation and the development of AF in ...

INTRODUCTION AND AIM About 15% of hyperthyroid patients suffer from gastrointestinal symptoms such as diarrhea, constipation, nausea and early satiety the problem. Published reports on the topic of gastric emptying in hyperthyroidism are rare and discrepant in their results. PATIENTS AND METHODS Thirteen patients (8 women, 5 male; aged 41.92+/-1.491 SE yr) with a recently established diagnosi...

Experimental hyperthyroidism has been demonstrated to influence insulin-stimulated glucose utilization in isolated skeletal muscle preparations from fed or starved rats, with increased glycogen-glucose < 1 -phosphate cycling [ I ] and diversion of carbon from net glycogenesis (storage) to glycolysis (degradation) [2]. The present study investigated whether this effect of hyperthywidism is also ...

Hepatic dysfunction is commonly observed in subjects with hyperthyroidism. Hepassocin a hepatokine playing an important role metabolic diseases and exhibiting hepatic protective effect. Nevertheless, the relationship between hepassocin hyperthyroidism was still unknown. In present study, total of 36 Graves’ disease were enrolled, we found that alanine aminotransferase (ALT) levels significantly...

OBJECTIVE The association between thyroid disease and breast cancer risk remains unclear. We, therefore examined the association between hypothyroidism, hyperthyroidism and breast cancer risk. DESIGN This was a population-based cohort study. METHODS Using nationwide registries, we identified all women in Denmark with a first-time hospital diagnosis of hypothyroidism or hyperthyroidism, 1978...

OBJECTIVES This study sought to prospectively evaluate the prevalence of cardiovascular abnormalities in patients with overt hyperthyroidism before and after antithyroid therapy. BACKGROUND Overt hyperthyroidism is associated with recognized cardiovascular effects believed to be reversed by antithyroid therapy; however, increasing data suggest significant long-term cardiovascular mortality. ...

Cardiovascular complications during hyperthyroidism are dominated by arrhythmias, heart failure and coronary disease. Pericardial effusion which is a common complication of hypothyroidism extremely rare in hyperthyroidism. We report the case 45-year-old woman admitted for management pleuro-pericarditis associated with atrial fibrillation context cardiothyreosis. The treatment consisted pericard...

Thyroid dysfunction is related to many kidney diseases. We herein present the case of a 39-year-old woman who exhibited obesity-related glomerulopathy-like pathologic features in combination with hyperthyroidism. She displayed hyperthyroidism in spite of receiving anti-thyroid drug treatment, with massive proteinuria (4.5 g/gCr). A renal biopsy demonstrated glomerular hypertrophy (average diame...

All cases of familial thyrotoxicosis with absence of evidence of autoimmunity and all children with persistent isolated neonatal hyperthyroidism should be evaluated for familial non-autoimmune autosomal dominant hyperthyroidism (FNAH) or persistent sporadic non-autoimmune hyperthyroidism (PSNAH). First, all index patients should be analysed for the presence/absence of a thyroid-stimulating horm...