It is often necessary to assess physical function in older adults to monitor disease progression, rehabilitation or decline in function with age. However, increasing frailty and poor balance that accompany aging are common barriers to exercise testing protocols. We investigated whether a 6-min stepper test (6MST) was acceptable to older adults and provided a measure of exercise capacity and a p...

Re-valuated instrumental magnitudes and intensity distributions for the Mw8.0 Shillong Plateau earthquake of 1897 and the Mw7.8 Kangra earthquake of 1905, combined with newly available geodetic constraints on rupture geometries, allow us to compare observed distributions of intensity with those predicted from theoretical models for shaking produced by each earthquake. The difference between pre...

If high-redshift QSOs are ejected from the nuclei of low-redshift galaxies, as some have claimed, a large portion of their redshift must be intrinsic (non-Doppler). If these intrinsic components have preferred values, redshifts will tend to cluster around these preferred values and produce peaks in the redshift distribution. Doppler ejection and Hubble flow components will broaden each peak. Be...

W develop a global equilibrium asset pricing model assuming that investors suffer from foreign aversion, a preference for home assets based on familiarity. Using a utility formulation inspired by regret theory, we derive closed-form solutions. When the degree of foreign aversion is high in a given country, investors place a high valuation on domestic equity, which results in a low expected retu...

PURPOSE The practice of intentional rounding up of serum creatinine (SCr) in elderly patients with low measured values can lead to an underestimation of creatinine clearance and subsequent inaccurate dosing of medications. Thus, the purpose of this study was to evaluate the accuracy of vancomycin dose calculations for patients aged ≥65 years using an SCr rounded up to 1 mg/dL versus actual SCr....

Currently, the influenza vaccine is updated only when there is at least a 4-fold difference [measured by the hemagglutination inhibition (HI) assay] between the current vaccine strain and an expected epidemic strain. It is not clear if this is the optimal strategy, especially for individuals vaccinated every year. Using a computer model, we determined the vaccine efficacy resulting from 12 diff...