BACKGROUND The goal of this study was to explore the relation between oxygen kinetics during constant work load submaximal cardiopulmonary exercise test (CPET) and disease severity in adult subjects with cystic fibrosis. METHODS Fourteen adult subjects with cystic fibrosis (CF; 8 males, 22 ± 4 y old) and a mean Schwachman score of 73 ± 11 and 10 healthy individuals (5 males, 29 ± 4 y old) und...

1.5 CPET Protocols Cardiopulmonary exercise testing (CPET) provides a global as-1.6 Treatment of the Data sessment of the integrative exercise responses involving the pul-1.7 Validation monary, cardiovascular, hematopoietic, neuropsychological, and 1.8 Statistical Treatment of the Data skeletal muscle systems, which are not adequately reflected 2. Alternative Approach to Obtain Normal Reference...

I read your article with interest. However, a sentence under the subheading ‘Cardiopulmonary exercise testing’ in the methods section (‘Two key measurements can be determined from these data, [oxygen uptake at peak exercise and anaerobic threshold], indicating the point at which anaerobic metabolism is inadequate to maintain high energy phosphate production [...]’) does not coincide with the pr...

A case of congenital, unilateral absence of a left pulmonary artery is described in a patient presenting with exertional dyspnea. Data from cardiopulmonary exercise testing suggest that the mechanism of dyspnea is secondary to a paradoxic elevation of the physiologic dead space to tidal volume ratio (VD/VT) during exercise.

STUDY OBJECTIVE To determine whether rapid-incremental work rate (IWR) testing would be as useful as standard high-intensity constant work rate (CWR) protocols in eliciting exercise-induced bronchoconstriction (EIB) in susceptible subjects. DESIGN AND SETTING A cross-sectional study performed in a clinical laboratory of a tertiary, university-based center. SUBJECTS AND MEASUREMENTS Fifty-ei...

OBJECTIVE The identification of populational levels of maximum oxygen uptake (VO(2max)) is an aid to studies that propose to relate physical fitness to cardiovascular risk, and also for prescribing exercise and analyzing the effects of training. To date, there is no information with which this parameter can be classified in samples of adolescents from the Brazilian population. This study is, th...

Standards for the use of cardiopulmonary exercise testing for the functional evaluation of cardiac patients: a report from the Exercise Physiology Section of the European Association of Cardiovascular Prevention and Rehabilitation Alessandro Mezzani, Piergiuseppe Agostoni, Alain Cohen-Solal, Ugo Corrà, Anna Jegier, Evangelia Kouidi, Sanja Mazic, Philippe Meurin, Massimo Piepoli, Attila Simon, C...

Mental stress induces transient endothelial dysfunction, which is an important finding for subjects at cardiometabolic risk. Thus, we tested whether aerobic exercise prevents this dysfunction among subjects with metabolic syndrome (MetS) and whether an increase in shear rate during exercise plays a role in this phenomenon. Subjects with MetS participated in two protocols. In protocol 1 (n = 16)...

We have investigated the effect of moderate and strenuous exercise on experimental arterial thrombus formation in men. Thrombogenesis was measured in 15 sedentary healthy male volunteers at rest or immediately after two standardized exercise tests performed for 30 min on a bicycle ergometer. The exercises were performed at a constant load corresponding to either 50 or 70% maximal oxygen uptake....

Background. Morbidity and mortality are higher in patients with poor preoperative cardiorespiratory reserve. This study aimed to ascertain fitness and therefore risk in elective patients, comparing three measures: Duke Activity Status Index (DASI) questionnaire, incremental shuttle walk test (ISWT), and cycle cardiopulmonary exercise testing (CPET). We looked for correlation between the measure...