Atomoxetine is a nonstimulant medication shown to be efficacious in the treatment of attention-deficit/hyperactivity disorder (ADHD). There have been no reports to date of tics being precipitated or exacerbated by atomoxetine. We report four patients with ADHD who had developed tics on stimulants and in whom tics reappeared or were exacerbated on atomoxetine. Moreover, the tics resolved or abat...

Correction for 'Charge-tunnelling and self-trapping: common origins for blinking, grey-state emission and photoluminescence enhancement in semiconductor quantum dots' by M. A. Osborne, et al., Nanoscale, 2016, 8, 9272-9283.

Since its initial discovery just over a decade ago, blinking of semiconductor nanocrystals has typically been described in terms of probability distributions for durations of bright, or "on," states and dark, or "off," states. These distributions are obtained by binning photon counts in order to construct a time series for emission intensity and then applying a threshold to distinguish on state...

We use anisotropic optical tracers (also called magnetically modulated optical nanoprobes – MagMOONs or MOONs for non-magnetic nanoprobes in this dissertation) to study biophysical processes such as enzyme-catalyzed cleavage through tissue, intracellular transport of these tracers and cytotoxicity based on this transport. The anisotropic optical properties cause these tracers to blink when rota...

iii-The manifold exciting applications of fluorescence in biophysics, nano-technology or super-resolution microscopy, pose extraordinary and multiple demands on the (single) organic dye molecules employed. A high extinction coefficient together with a high fluorescence quantum yield and water-solubility are nowadays considered as standard properties of suitable organic dyes. However, single-mol...

This paper examines methods to test one- and two-dimensional histograms for several features including the renewal properties, detailed balance violations, and experimental condition dependences. The tests are simple to implement and allow rigorous statistical determination of the existence of these kinetic features. The tests are used to determine the lower bound on the number of measurements ...

An automatic model is presented for animating gaze shifts of virtual characters towards target locations in a virtual environment. Two connected components are described: an eye–head controller and a blinking controller. The gaze control model is based on results from neuroscience, and dictates the contributions of the eyes and head to a gaze shift according to an individual’s head movement pro...

Previous work has found that search principles derived from simple visual search tasks do not necessarily apply to more complex search tasks. Using a Multielement Asynchronous Dynamic (MAD) visual search task, in which high numbers of stimuli could either be moving, stationary, and/or changing in luminance, Kunar and Watson (M. A Kunar & D. G. Watson, 2011, Visual search in a Multi-element Asyn...

High particle uniformity, high photoluminescence quantum yields, narrow and symmetric emission spectral lineshapes and minimal single dot emission intermittency (known as blinking) have been recognized as universal requirements for the successful use of colloidal quantum dots (QDs) in nearly all optical applications. However, synthesizing samples that simultaneously meet all these four criteria...