BACKGROUND Alterations in extracellular vesicles (EVs), including exosomes and microparticles, contribute to cardiovascular disease. We hypothesized that obesity could favour enhanced release of EVs from adipose tissue, and thereby contribute to cardiovascular risk via obesity-induced metabolic complications. The objectives of this study were: 1) to investigate the relation between the quantity...

Enterovirus A71 (EV-A71) is one of the main causative agents of hand, foot and mouth disease (HFMD). Unlike other enteroviruses that cause HFMD, EV-A71 is more frequently associated with severe neurological complications and fatality. To date, no effective licensed antivirals are available to combat EV-A71 infection. Little is known about the immunogenicity of viral non-structural proteins in h...

Signature of Randall-Sundrum Quantum Gravity model in γγ scattering in the TeV range. Abstract We examine the implications of the Randall-Sundrum gravity models on γγ scattering in the TeV range. It has recently been proposed that the scale of weak interactions M ∼ 1T eV is the only fundamental scale of energy in the description of particle interactions. The conventional scale of gravitational ...

Enteroviruses (EVs) are common seasonal viruses that are associated with a variety of diseases. High-quality monoclonal antibodies (MAbs) are needed to improve the accuracy of EV diagnosis in clinical laboratories. In the present study, the full-length VP1 genes of poliovirus 1 (Polio 1) and coxsackievirus B3 (Cox B3) were cloned, and the encoded proteins were expressed and used as antigens in ...

BACKGROUND Several enterovirus (EV) genotypes can result in aseptic meningitis, but their routes of access to the central nervous system remain to be elucidated and may differ between the pediatric and adult populations. OBJECTIVE To assess the pattern of viral shedding in pediatric and adult subjects with acute EV meningitis and to generate EV surveillance data for Switzerland. STUDY DESIG...

This paper introduces EV Meta-Model, a new system for representing musical knowledge for computer-aided composition. It starts with a brief historical discussion on the fields of composition and sound synthesis. Then, the practice of musical composition is presented as a communication process from composers to listeners, where musical messages go through different representations: from the comp...

not conclusive, it suggests an alternative model of TEL-AML1 leukemogenesis (see figure, Model B). In this model, the initiating event (TEL-AML1 fusion) is as rare as the disease itself, implying that a high proportion (perhaps 100%) of babies born with a detectable TEL-AML1 fusion are destined to develop TEL-AML1 ALL. Could newborn screening for TEL-AML1 be considered in this scenario? Assumin...

calcium carbonate nano-particles were synthesized by a reverse micro-emulsion method at room temperature with tween® 80 and span® 80 as co-surfactants. the nano-particles synthesized were surface modified by stearic acid. an important operating variable in the span 80-tween 80/toluene/water reverse micro-emulsion system, the ω-value (water/surfactant molar ratio) was investigated. the material ...