Beneficial effect of eugenol on fatty liver was examined in hepatocytes and liver tissue of high fat diet (HFD)-fed C57BL/6J mice. To induce a fatty liver, palmitic acid or isolated hepatocytes from HFD-fed Sprague-Dawley (SD) rats were used in vitro studies, and C57BL/6J mice were fed HFD for 10 weeks. Lipid contents were markedly decreased when hepatocytes were treated with eugenol for up to ...

The Ca(2+)-activated Cl(-) channel TMEM16A is involved in epithelial fluid secretion, smooth muscle contraction and neurosensory signaling. We identified a Thai herbal antidiarrheal formulation that inhibited TMEM16A Cl(-) conductance. C18-reversed-phase HPLC fractionation of the herbal formulation revealed >98% of TMEM16A inhibition activity in one out of approximately 20 distinct peaks. The p...

Background: Dry socket is the most common post-operative complication following extraction of teeth. Various risk factors have been mentioned for this complication including gender, age, amount of trauma during extraction, difficulty of surgery, inappropriate irrigation, infection, smoking, and oral contraceptive use. Traditional treatment of dry socket require frequent visit of patient to the ...

In this study, computed tomography (CT) was used to assess three techniques for root canal filling removal. Seventy-five roots of extracted human lower incisors were filled with zinc oxide-eugenol sealer and gutta-percha and separated into three groups before gutta-percha removal (group 1, Gates Glidden burs + K-type hand instrumentation; group 2, K-type reciprocating instrumentation + NSK TEP ...

INTRODUCTION Various materials and methods have been recommended for successful root canal obturation. The aim of this experimental in vitro study was to compare the sealing ability of three root canal sealers AH-26, glass ionomer cement (GIC) and zinc oxide eugenol (ZOE) in single gutta-percha obturating system. METHODS AND MATERIALS Seventy extracted single-rooted human teeth were decoronat...

We report on the fabrication of thin coatings based on polylactic acid-chitosan-magnetite-eugenol (PLA-CS-Fe3O4@EUG) nanospheres by matrix assisted pulsed laser evaporation (MAPLE). Transmission electron microscopy (TEM) and scanning electron microscopy (SEM) investigation proved that the homogenous Fe3O4@EUG nanoparticles have an average diameter of about 7 nm, while the PLA-CS-Fe3O4@EUG nanos...

This in vivo study evaluated the sealing ability of a resin-based sealer (AH Plus) and a zinc oxide-eugenol sealer (Endofill) in dogs' teeth, exposed to the oral environment for 45 and 90 days. Forty eight lower incisors from 8 dogs were endodonticaly treated. A stratified randomization determined the sealer use in each root canal. All canals were filled using the lateral condensation technique...

Eugenol is the active molecule naturally found in clove oil. The calculations have been done for eugenol and its derivatives computationally. This computational calculation aims to obtain a stable structure electronic properties of eugenol, methyl acetyl eugenol. used DFT geometry optimization gas phase using B3LYP functional 6-31G(d) as basis set. optimized not planar. presence methoxy replaci...

Olfactory perception is characterized by interpersonal variability. Although gender has been identified as a potential influencing factor, currently little is known about its effect on perceived hedonicity of individual odorants. This study assessed gender differences in emotional appraisal of 3 odorants (eugenol, vanillin, and hydrogen sulfide [H(2)S]), presented to 25 healthy subjects (13 mal...