INTRODUCTION The use and clinical efficacy of the alcohol dehydrogenase inhibitor fomepizole is well established for the treatment of ethylene glycol and methanol poisonings in adults. METHODS A computerized search of the U.S. National Academy of medicine and EMBase databases was undertaken to identify published cases of patients treated with fomepizole. This search strategy identified 14 pub...

Considerable interest has recently been evoked in the study of proteins in nonaqueous solvents, very largely as a result of the observations of Rees and Singer (1) and Yang and Doty (2) that the internal configuration of protein molecules could be radically altered in nonaqueous media, as reflected by changes in sedimentation constants, viscosity increments, and optical rotatory dispersion. Of ...

Frothers havea profoundeffectonbubble size and also flotation efficiency. In present study the effect of type and dosage of frothers on the flotation response of coarse particles of quartz was investigated.  Therefore, flotation response of coarse particles using frothers such as MIBC, pine oil, poly propylene glycol with concentration of 0, 25, 50 and 75...

Background This study aimed to determine effects of synbiotics on treatment of functional constipation in children aged 2-10 years old. Materials and Methods This randomized single blind clinical trial study carried out on children who had functional constipation based on the Rome III criteria. The  polyethylene glycol + synbiotic group (P+S group, n=38)received the synbiotic with polyethylene ...

although antidote development should proceed in an orderly fashion from observation, to experimental and safety studies, to clinical trials, this sequence is not always precisely followed. the development of fomepizole as an antidote for toxic alcohol and glycol poisoning is an example of how this may not be the case. interest in the development of fomepizole was spurred in the 1960s. shortly t...

to determine the effects of priming and planting density on improvement of morphological and physiological traits of the two hybrid corns sc (s.c. 704) under double cropping in sari, a split plot experiment as randomized complete block design with four replications was conducted in 2010. treatments included two densities of 80 and 100 thousand plants per hectare as the first factor and osmoprim...

A gram-negative nonmotile rod which was capable of using 1,2-(14)C-ethylene glycol as a sole carbon source for growth was isolated from a brine pond, Great Salt Lake, Utah. The bacterium (ATCC 27042) required at least 0.85% NaCl for growth and, although the chloride ion was replaceable by sulfate ion, the sodium ion was not replaceable by potassium ion. The maximal concentration of salt tolerat...

Is the recently found seepage groundwater on Mars pure H2O, or mixed with salts and other antifreeze compounds? Given the surface conditions of Mars, it is unlikely that pure water could either exist in its liquid state or have shaped Mars’ fluid erosional landforms (gullies, channels, and valley networks). More likely is that Mars’ seepage groundwater contains antifreeze and salt compounds tha...

The main goal of this study was to describe the method of the synthesis of the dodecyl-, tetradecyl-, hexadecyl- and octadecyl-propylene glycol emulsifiers in the presence of selected anionic and nonionic surfactants. Acyl propylene glycol emulsifiers were produced by esterification of propane-1,2-diol (propylene glycol, PG) with C12:0-C18:0 fatty acids in the presence of anionic sodium dodecyl...

The early literature indicates much confusion as to the origin of acetylmethylcarbinol and butylene glycol in microbiological fermentations. Happold and Spencer (1) have reviewed much of this early work and have studied in detail the conditions for the formation of acetylmethylcarbinol and butylene glycol from glucose and pyruvate by Aerobacter aerogenes. Juni (2) has demonstrated that acetoin ...