We read the article entitled “Depression is associated with increased C-reactive protein levels in patients with heart failure and hyperuricemia”. In this article WANG, et al. reported that serum hs-CRP may be an independent marker for severity of depression in heart failure patients with hyperuricemia. The authors suggested that the relationship between the role of inflammation in the pathogen...

Insulin and glucose have long been known to be effective in experimental heart failure but there is still surprisingly little knowledge of their effects on cardiac function in man. Reawakening of interest in this relation has been occasioned by two recent findings. Firstly, the critical role of glucose in the metabolism of the failing anoxic heart has been precisely defined (Scheuer, I967; Weis...

1 Piepoli MF, Ponikowski PP, Volterrani M, et al. Aetiology and pathophysiological implications of oscillatory ventilation at rest and during exercise in chronic heart failure. Do Cheyne and Stokes have an important message for modern-day patients with heart failure? Eur Heart J 1999;20:946–53. 2 Vangesselen S, Weymans M, Mertens L, et al. A Java software for calculating mean breath-by-breath v...

Acute kidney injury (AKI) is a clinical syndrome denoted by an abrupt decline in glomerular filtration rate (GFR) sufficient to decrease the elimination of nitrogenous waste products (urea and creatinine) and other uremic toxins (Jefferson et al, 2010). AKI is a not very common yet serious complication occurring in pregnancy. The incidence and the mortality rates associated with obstetric acute...

breathlessness. J Pain Symptom Manage 2013; 46: 957–963. 10 Abernethy AP, Currow DC, Frith P, et al. Randomised, double blind, placebo controlled crossover trial of sustained release morphine for the management of refractory dyspnoea. BMJ 2003; 327: 523–528. 11 Johnson MJ, McDonagh TA, Harkness A, et al. Morphine for the relief of breathlessness in patients with chronic heart failure–a pilot st...

Better Predictors of Heart Failure Mortality Than Peak Exercise Oxygen Consumption To the Editor: We read with great interest the article by Robbins et al1 describing how exercise-related ventilatory and heart rate responses better predict heart failure mortality than peak exercise oxygen consumption.2 Although Robbins et al1 correctly state that other investigators have shown that exercise-rel...

To the Editor: I read with great interest the review by Yamamoto et al about “heart failure with preserved ejection fraction–what is known and unknown”. 1 However, some evidence about pharmacological therapy in this group is not included in this article. An increasing number of patients with heart failure are diagnosed with preserved left ventricular ejection fraction (PLVEF). The prevalence of...

Fault localization can be used to prioritize the statements of a program according to the likelihood that each contains a fault that causes a known failure [Jones et al. 2002; Renieres and Reiss 2003]. Regression test prioritization is used to order statements according to early achievement of some testing goal such as coverage [Elbaum et al. 2000; Li et al. 2007; Rothermel et al. 2001; Yoo and...

British Journal of General Practice, March 2007 and want improved information? Patient Educ Couns 2001; 45(3): 181–185. 5. Murray SA, Boyd K, Kendall M, et al. Dying of lung cancer or cardiac failure: prospective qualitative interview study of patients and their carers in the community. BMJ 2002; 325(7370): 929. 6. Rogers AE, Addington-Hall JM, Abery AJ, et al. Knowledge and communication diffi...