the objective of this work is to elucidate various essential drugs in the brazil, russia, india, china and south africa (brics) countries. it discusses the opportunities and challenges of the existing biotech infrastructure and the production of drugs and vaccines in member states of the brics. this research is based on a systematic literature review between the years 2000 and 2014 of documents...

Background and objectives: Several natural compounds have been identified for the treatment ofleishmaniasis. Due to a few safe drugs and the side effects caused by available chemotherapy, some new drugs for treatment of leishmaniasis are requested.  The genus Pulicaria (Asteraceae) is represented in the flora of Iran by five species. Phytochemical studies on Pulicaria...

Understanding the mode of action antimalarials is central to optimizing their use and discovery new therapeutics. Currently used belong a limited series chemical structures mechanisms are coutinuously debated. Whereas involvement reactive species that in turn kill parasites sensitive oxidative stress, accepted for artemisinins, little known about generation such case quinolines or hydroxynaphto...

The appearance of antifungal resistance promotes the investigation therapeutic options. There are few studies on combined effect drugs and essential oils (EOs). In present work, regarding association eight EOs Andean plants with agents against a panel fungi strains. Combinatorial effects were determined using Fractional Inhibitory Concentration Index (FICI) Dose Reduction (DRI). A combination A...

BACKGROUND The Candida species are the most important factors of fungal infections in humans and animals. It is necessary to prepare antifungal or antimicrobial drugs because of increasing drug resistance. The natural treatment of diseases of bacterial origin using medicinal plants is important. In this study the effect of antimicrobial medicinal herbal essential oils and conventional antifunga...