We present a female patient manifested by AIH associated with systemic lupus erythematosus related antiphospholipid syndrome.

The main objective of this study is to describe the presence of infections in patients with pulmonary haemorrhage and systemic lupus erythematosus. Patients with systemic lupus erythematosus and pulmonary haemorrhage were thoroughly evaluated in the first 48 hours with imaging plus bronchoscopy and bronchoalveolar fluid analysis. If needed, videoassisted thoracoscopy and lung biopsy were perfor...

Systemic Lupus Erythematosus is a chronic inflammatory disease with multifactorial etiology. Although clinical manifestations are varied, the skin is an important target-organ, which contributes to the inclusion of skin lesions in 4 out of the 17 new criteria for the diagnosis of the disease, according to the Systemic Lupus International Collaborating Clinics. The cutaneous manifestations of lu...

This study investigated the use of anti-ribosomal P antibodies in the diagnosis of cerebral complications of systemic lupus erythematosus using two different methods---western blotting and enzyme-linked immunosorbent assay. Anti-ribosomal P antibodies in patient serum were detected in both methods using a purified ribosomal P antigen substrate. Western blotting detected anti-ribosomal P antibod...

The parotid gland may enlarge during the course of systemic lupus erythematosus (SLE). Shearn and Pirofsky (1952) were the first to draw attention to this association while studying a group of 34 patients who had systemic lupus erythematosus. They discovered sialoadenitis characterized by chronic, nonsuppurative inflammation unilaterally in one and bilaterally in two patients. Morgan (1954) rep...

A sixteen year old girl with systemic lupus erythematosus developed acute transverse myelopathy. She was treated with high dose steroids, cyclophosphamide, and plasma exchange and regained partial neurological function. Previous descriptions of transverse myelopathy complicating systemic lupus erythematosus are reviewed, with particular reference to the efficacy of high dose steroid treatment.

131 ISSN 1758-4272 10.2217/IJR.11.81 © 2012 Future Medicine Ltd Int. J. Clin. Rheumatol. (2012) 7(2), 131–134 “Renal pathologists should be aware of the histologic characteristics of antiphospholipid syndrome-associated nephropathy when they examine kidney biopsies of systemic lupus erythematosus patients, especially those with positive antiphospholipid antibodies.” Antiphospholipid syndrome-as...

Two cases of subacute cutaneous lupus erythematosus are described. Features which delayed diagnosis are discussed. The potential clinical and histopathological overlap between this condition and erythema multiforme is emphasized, drawing attention to the histological features which allow distinction. The possibility that some cases of Rowell's syndrome may be manifestations of subacute lupus er...

Case records of the Massachusetts General Hospital. Case 39-2006. A 24-year-old woman with systemic lupus erythematosus, seizures, and right arm weakness.Case records of the Massachusetts General Hospital. Case 39-2006. A 24-year-old woman with systemic lupus erythematosus, seizures, and right arm weakness.

The chronic inflammatory environment associated with systemic lupus erythematosus can lead to an accelerated immunosenescence responsible for the endothelial damage and increased cardiovascular risk observed in these patients. The present study analyzed two populations with opposite effects on vascular endothelium, angiogenic T cells and the senescent CD4(+)CD28(null) subset, in 84 systemic lup...