Surface mechanomyographic (MMG) signals have been detected during various types of dynamic muscle actions, including dynamic constant external resistance (DCER) muscle actions, concentric and eccentric isokinetic muscle actions, as well as incremental and constant power output cycle ergometry. Although the MMG amplitude and center frequency [mean power frequency (MPF) or median frequency] respo...

The technique of non-invasive blood pressure monitoring was used to compare the 24-hr control of blood pressure in 10 patients with essential hypertension taking either twice daily propranolol or a once daily long-acting formulation of propranolol (propranolol LA). Both drug regimes produced smooth control of blood pressure and heart rate through the 24 hours and significantly reduced blood pre...

Introduction We studied the reliability of a new ST-segment analysis on a 24-hour 12-lead holter recording comparing ST-depression during exercise testing with active molsidomine and placebo drugs in a randomized, double-blind, crossover, clinical trial. Methods and results 35 patients with proven coronary heart disease received either 4 mg regular molsidomine, 8 mg molsidomine SR (Sustained Re...

Abnormal calcium transport may be implicated in the membrane defect in myotonic dystrophy. A single blind crossover trial of placebo (t.i.d.), nifedipine 10 mg (t.i.d.) and nifedipine 20 mg (t.i.d.), was performed in 10 patients with myotonic dystrophy. The severity of myotonia was assessed by measuring finger extension time after maximum voluntary finger flexion. A significant improvement in m...

Theoretically, the electromyographic (EMG) fatigue threshold is the exercise intensity an individual can maintain indefinitely without the need to recruit more motor units which is associated with an increase in the EMG amplitude. Although different protocols have been used to estimate the EMG fatigue threshold they require multiple visits which are impractical for a clinical setting. Here, we ...