introduction: the aim of this study was to evaluate the composite surface treated by different powers of erbium-doped yttrium aluminum garnet (er:yag) laser in comparison with bur preparation via scanning electron microscope. methods: fourteen composite resin blocks with 15× 10 × 10 mm dimensions were used in this study. the samples were divided to seven groups as follow: group 1 (power: 1 w, e...

introduction :the aim of this study was to evaluate and compare the in vitro effect of the erbium-doped yttrium aluminum garnet (er:yag) laser with different radiation distances and high-speed rotary treatment on the shear bond strength of flowable composite to enamel of human permanent posterior teeth . methods : freshly extracted human molar teeth with no caries or other surface defects were ...

background: use of hormone replacement therapy (hrt) may increase the risk of adult-onset asthma in women. various in vitro studies have reported that estradiol stimulates human mast cell lines causing release of allergic mediators which was not observed in estrogen receptor-alpha (er-alpha) knockout mice. thus, estrogen might be a key element in occurrence of asthma. in the present study, we p...

Trichodysplasia spinulosa (TS) is a rare hair follicle disorder that develops in immunosuppressed patients and associated with productive infection by the TSPyV polyomavirus. Affected follicles contain an attenuated matrix, expanded compartment of aberrantly proliferating inner root sheath (IRS)-like cells containing viral particles, disorganized mass shaft-like cells. The expression early regi...

Distinct spatiotemporal Ca2+ signalling events regulate fundamental aspects of eukaryotic cell physiology. Complex Ca2+ signals can be driven by release of Ca2+ from intracellular organelles that sequester Ca2+ such as the ER (endoplasmic reticulum) or through the opening of Ca2+-permeable channels in the plasma membrane and influx of extracellular Ca2+. Late endocytic pathway compartments incl...

3'-Untranslated region (UTR) shortening of mRNAs via alternative polyadenylation (APA) has important ramifications for gene expression. By using proximal APA sites and switching to shorter 3'-UTRs, proliferating cells avoid miRNA-mediated repression. Such APA and 3'-UTR shortening events may explain the basis of some of the proto-oncogene activation cases observed in cancer cells. In this study...

BACKGROUND This study aims to evaluate the efficacy of Er,Cr:YSGG laser assisted periodontal therapy on the reduction of oral malodor and periodontal disease. METHODS Sixty patients with chronic periodontitis were included in the study and allocated into two groups each containing 30 patients. The study was planned in a double blind fashion. Conventional periodontal therapy was performed in g...

The activity of estradiol on the LHRH neuronal network is crucial in the regulation of reproduction. In vivo, estradiol induces galanin (GAL) gene expression in LHRH neurons and GAL/LHRH colocalization is sexually dimorphic and neonatally determined by steroid exposure. The effects of estradiol on LHRH neurons, however, are considered to be indirect because estrogen receptors (ER) have not been...

Background: Lichen planus is a T-cell mediated autoimmune and chronic inflammatory disease that affects the skin and the mucous membrane. The results of numerous studies on oral mucosa have confirmed the effects of sex hormones on oral mucosa and the expression of estrogen (ER), progesterone (PR), and androgen receptors. Lichen planus is a common disease in middle-aged wo...