conclusions our findings introduced a novel therapeutic effect of diet therapy on circulating mirnas in obese patients with t2dm. mir-33b is an important therapeutic target in the treatment and prevention of t2dm and its complications. results the circulating levels of mir-29a and mir-33b in the diabetic women were higher (0.40-fold) and lower (1.43-fold), respectively, than normal levels. diet...

1833 Elevated levels of circulating high-density lipoprotein cholesterol (HDL-C) have long been thought to be associated with reduced coronary artery disease (CAD) risk. This concept has led to the HDL hypothesis: increasing HDL-C would be a key addendum in the prevention of CAD, in addition to reducing circulating low-density lipoprotein cholesterol levels. In theory, increasing HDL-C should i...

For a mechanical perturbation, the microscopic response method is equivalent to and more convenient to use than the Kubo formula. When the gradient of the carrier density is small, the current density reduces to that used by Greenwood.

where q is the jz net charge (q < 0 for excess electron density) on the adjacent carbon atom. A value of a = 10.7 ppm/electron has been obtained [4] by a re­ gression analysis between observed shifts and net charges in the diatropic [5] annulenes C5H 5_ , C6H6, C 7H 7+, and C 8H 82~. Herewith it was assumed that RC and L A terms do not differ considerably in these compounds and that the counter...

Colle and Salvetti @Theor. Chim. Acta 37, 329 ~1975!# approximated the correlation energy of a manyelectron system as a functional of the Hartree-Fock one-particle density matrix. The most fundamental and least approximate version of this functional @their Eq. ~9!# is found to yield only 25% of the true correlation energy of a uniform electron gas, and not 100% as previously believed. While sho...

The low density lipoprotein particle is the major transporter of cholesterol around the body and has been shown to be a strong independent risk factor for atherosclerotic events. This review discusses the normal and abnormal metabolism of low density lipoprotein (LDL). Mechanisms by which LDL causes atherosclerosis are discussed with particular reference to the importance of alteration in LDL c...

OBJECTIVE To compare paraoxonase activity and changes in oxidative status in asthmatic children and healthy children by determining serum paraoxonase activity and total oxidative status, total antioxidant capacity and lipid hydroperoxidation. METHODS Forty two asthmatic children were compared with 32 healthy children of similar age and sex. To evaluate the paraoxonase and oxidative status, to...