Being widely used, medicinal products based on vegetable oils require strict regulation and evaluation of quality attributes, determination shelf-life periods, monitoring storage conditions. The most common testing method for unsaturated compounds in is the iodine value determination, which has a range limitations. An alternative determining degree unsaturation epoxidation. aim study was to eva...

Asymmetric epoxidation is one of the most important transformations in organic synthesis. Although tremendous progress was achieved in this field in the 1980s and 1990s, it is still desirable from both economical and ecological views to develop environmentally friendly catalytic epoxidation with a broad substrate scope. Hydrogen peroxide is a safe and cheap oxidant, which is easy to handle and ...

Presented are density functional calculations on various Mn(salen) systems that are active catalysts in the epoxidation of olefins. Correlation of various structural properties such as Mn=O bond strengths, atomic charges, and C-O distances of evolving bonds in transition state geometries with modified Hammett constants reveal a mechanistic picture of the epoxidation reaction, supporting previou...

The reactions of sec-aminodienyl esters 3 with acetylacetone (4) afforded N-alkyl 3-acetyl-4-methoxycarbonylmethyl-2-methyl-1,4-dihydropyridines 5 and enamines 6, providing a new azaelectrocyclization reaction.

A facile and convenient protocol was developed for the fast (2.5-3.5 h) and high yielding (70-90%) synthesis of fused 1,4-dihydropyridines from dimedone in the presence of HY-zeolite as an efficient recyclable heterogeneous catalyst.

The ethoxycarbonylmethyl esters of 1,4-dihydropyridines were directly converted into carbamoylmethyl esters in the presence of 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) in good to excellent yields under mild conditions. The use of TBD is crucial for the successful aminolysis of ethoxycarbonylmethyl ester of 1,4-dihydropyridines with secondary amines as without it the reaction does not proceed a...

Gold(I)-catalyzed nucleophilic allylations of pyridinium and quinolinium ions with various allyl pinacolboronates are reported. The reactions completely selective respect to the site azinium ion that is attacked, give functionalized 1,4-dihydropyridines 1,4-dihydroquinolines. Evidence suggests proceed through allylgold(I) intermediates formed by transmetalation from allylboronates. Density func...

The surface of magnetite nanoparticles as nano-sized solid support was modified with a molybdenum-Schiff base complex to prepare an easily separable heterogeneous catalyst for the epoxidation of olefins. Characterization techniques such as Fourier transform infrared and inductively coupled plasma optical emission spectroscopies, X-ray diffraction, vibrating sample magnetometry, scanning, an...

Abstract: Thiazole or 1,3-thiazole is a distinct heterocyclic compound which incorporates sulphur and nitrogen atoms. It vital framework present in numerous pharmacologically active compounds, be it of natural origin synthetic nature. Many thiazoles having antitumor antiviral activities, originate from microbes marine organisms. A variety drugs, thiazole group, like antimicrobial sulfathiazole,...