Plus-maze following the microinjection of muscimol into the dorsal periaqueductal gray of the rat Performance no labirinto em cruz elevado após microinjeção de muscimol na substância cinzenta periaquedutal dorsal do rato Dear Editor, Some experimental findings have indicated that the rat dorsal periaqueductal gray (DPAG) is part of a longitudinally organized neural system responsible for behavi...

conclusions ip injection of cb1 receptor antagonist might have an anxiogenic profile in rat, whereas calcium channel blocker attenuated the anxiogenic effect of am251. our results suggest that there is an interaction between functions of l-type ca2+ channels and cannabinoid system in anxiety. background the elevated plus-maze (epm) has been broadly used to investigate anxiolytic and anxiogenic ...

OBJECTIVES Most UK medical programmes use aptitude tests during student selection, but large-scale studies of predictive validity are rare. This study assesses the UK Clinical Aptitude Test (UKCAT: http://www.ukcat.ac.uk), and 4 of its subscales, along with individual and contextual socioeconomic background factors, as predictors of performance during, and on exit from, medical school. METHOD...

The role of serotonin (5-hydroxytryptamine [5-HT]) and 5-HT2A receptors in anxiety has been extensively studied, mostly without considering individual differences in trait anxiety. Our laboratory developed two lines of animals that are bred for high and low freezing responses to contextual cues that are previously associated with footshock (Carioca High-conditioned Freezing [CHF] and Carioca Lo...

Studies showing anxiolytic-like properties of natural products have grown. This paper evaluated if carvacryl acetate (CA) could be studied as an alternative drug to treat anxiety disorders. Elevated plus maze (EPM) tests , light-dark box (LDB) tests, and marble-burying tests (MBTs) were performed on mice. In the first protocol, the anxiolytic-like activities of CA 25, 50, 75 and 100mg/kg at sin...

Finding an accurate computational method for estimating pan evaporation (EPm) can be useful in the application of these methods development sustainable agricultural systems and water resources management. In present study, proposed hybrid called multiple model-support vector machine (MM-SVM) with aim showing increasing, decreasing, constant accuracy behavior this model improving results EP comp...

INTRODUCTION Previous studies have shown that cannabinoidergic system is involved in anxiety. However, there are controversial reports in the experimental studies. The aim of this study is to evaluate the effect of pharmacological stimulation or blocking of CB1 receptors and inhibition of endocannabinoid degradation in anxiety like behavior in elevated plus-maze (EPM) test in rat. The EPM is on...