Radiation-induced pulmonary injury (RIPI) is a common adverse reaction when ionizing radiation acts on the lung. Type II alveolar epithelial cells participate in process of RIPI by regulating inflammation, epithelial-mesenchymal transition, cellular senescence, etc. The expression miR-139-5p inhibited radiation, which plays role modulating radiotherapy resistance breast cancer tissues. PIEZO1, ...

Introduction: Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive and usually fatal lung disease of unknown etiology for which no effective treatments currently exist. In the adults type I and II pneumocytes, forms Components of the alveolar epithelial cells. In this study, we investigated the effect of thalidomide on the alveolar epithelial cells (type I and II pneumocytes) in ...

background: umbilical cord blood (ucb) is an alternative source of hematopoietic stem cell transplantation (hsct), used in leukemia treatment. cd26+ cells, a fraction of cd34 positive cells, are a major population of ucb cells which negatively regulate the in vivo homing and engraftment of hscs. cd26 is highly expressed in various cells such as hscs, immune cells, fibroblasts, and epithelial ce...

Background & Aims: Amniotic membrane persists for a long time after ocular transplantation (as corneal substitute) and can affect light transmission (transparency). The aim of this study was to evaluate the transparency of amniotic membrane after freeze-drying (lyophilization) and to compare the results with transparency of rabbit cornea. Methods: Transparency of rabbits’ corneas and fresh and ...

introduction: idiopathic pulmonary fibrosis (ipf) is a relentlessly progressive and usually fatal lung disease of unknown etiology for which no effective treatments currently exist. in the adults type i and ii pneumocytes, forms components of the alveolar epithelial cells. in this study, we investigated the effect of thalidomide on the alveolar epithelial cells (type i and ii pneumocytes) in th...

Diclofenac, the anti-inflammatory drug, is found in natural water bodies all over the world. Toxicological researches of diclofenac report harmful effects on aquatic species even at low concentrations. The aim of present study was to determine whether diclofenac affected on the gills, liver and kidney of common carp (Cyprinus carpio). In order to evaluate toxic effects of diclofenac as NASIDs (...

The structural differences between  dormant and nondormant seeds of wild oats (Avena ludoviciana Durieu) were studied by light and transmission electron microscopy. Radial elongation of  scutellum epithelial cells were observed in nondormant seeds after imbibition, compared with dormant seeds in which cells were completely compressed. Ultrastructural differences for example, dilution of cytopla...

Objective(s): Severe injuries are often associated with tissue hypothyroidism, elevated damaging mediators in circulation, and broken gut epithelial barrier.  However, the relationships between the hypothyroid state and gut epithelial damage are largely unknown.  Therefore, in this study, we investigated the effects of L-thyroxine (T4) on in vitro models of intact and ...