The development and extension of large cities induced a need for shallow tunnel in soft ground of building areas. Estimation of ground settlement caused by the tunnel excavation is important engineering point. In this paper, prediction of surface subsidence caused by tunneling in one section of seventh line of Tehran subway is considered. On the basis of studied geotechnical conditions of the r...

Endoplasmic reticulum (ER) stress-induced apoptosis is involved in many diseases, but the mechanisms linking ER stress to apoptosis are incompletely understood. Based on roles for C/EPB homologous protein (CHOP) and ER calcium release in apoptosis, we hypothesized that apoptosis involves the activation of inositol 1,4,5-triphosphate (IP3) receptor (IP3R) via CHOP-induced ERO1-alpha (ER oxidase ...

The discovery of the JAK2V617F mutation in most patients with Ph-negative myeloproliferative neoplasms has led to the development of JAK2 kinase inhibitors. However, JAK2 inhibitor therapy has shown limited efficacy and dose-limiting hematopoietic toxicities in clinical trials. In the present study, we describe the effects of vorinostat, a small-molecule inhibitor of histone deacetylase, agains...

Con el objeto de estimar efecto diferencial la sintomatología ansiosa-depresiva y impulsividad sobre los pensamientos suicidas en adolescentes función del tipo apoyo parental, se evaluaron a 440 estudiantes chilenos que cursaban estudios secundarios. Se administraron subescala ideación suicida Columbia-Suicide Severity Rating Scale (C-SSRS), las Escalas Abreviadas Depresión, Ansiedad Estrés (DA...

Chemical evaluation of the semi-purified fraction from the seeds of guaraná, Paullinia cupana H.B.K. var. sorbilis (Mart.) Ducke, yielded the following compounds: caffeine, catechin, epicatechin, ent-epicatechin, and procyanidins B1, B2, B3, B4, A2, and C1. Measurement of the antioxidant activity by reduction of the DPPH radical confirmed the anti-radical properties of the aqueous (AqE) and cru...

Here we give two examples of low-latitude plasma blobs accompanied by linearly polarized perpendicular magnetic deflections which imply that associated field-aligned currents (FACs) have a 2-D sheet structure located at the blob walls. The estimated FAC density is of the order of 0.1 μA/m2. The direction of magnetic deflections points westward of the magnetic meridian and there is a linear corr...

Abstract. This paper presents an overview and the current status of hosting the electrostatic plasma brake (EPB) experiment onboard the Finnish Aalto-1 satellite. The goal of the experiment is to demonstrate the use of an electrostatically charged tether for satellite attitude and orbital maneuvers. The plasma brake device is based on electrostatic solar sail concept, invented in Finnish Meteor...

During earth pressure balance (EPB) shield tunnelling in sandy ground, not only foam but also other conditioning agents need to be injected reduce the permeability of muck and avoid water spewing out screw conveyor. Permeability tests were carried study characteristics conditioned sand under high hydraulic gradients. A low bentonite slurry injection ratio (BIR) enhanced workability foam-conditi...