Patients with cardiovascular symptoms are mainly diagnosed in cardiological wards. However, sometimes the other reasons for acute coronary syndrome and heart failure are found. One of such reasons is hypereosinophilia which can be recognized if number of blood eosinophils exceeds 1500/mm3. High eosinophilia is connected with production of cytotoxic eosinophilic proteins which can cause eosinoph...

Eosinophilic granuloma was formerly mistaken for “eosinophilic myeloma” (Finzi 1929) or for “osteomyelitis with eosinophilic reaction” (Schairer 1938). It was described as a new distinct entity by Otani and Ehrlich (1940) under the denomination solitary granuloma of bone and by Jaffe and Lichtenstein (1944) as eosinophilic granuloma ofbone. Farber(l94l) and Green and Farber (1942) showed that e...

Address correspondence to: Dr. Chintan Modi, Saint Michael’s Medical Center, 111 Central Avenue, Newark, NJ 07102; Tel: 973-877-5351; Fax: 973-877-2984; E-mail: [email protected] The inflammatory fibroid polyp (IFP) is an uncommon benign tumor of the gastrointestinal tract. The tumor was first described in 1949 by Vanek as a gastric submucosal granuloma with eosinophilia.1,2 It has also been...

Over the last century, eosinophils have been regarded ambiguously either as ‘friends’ or ‘foes’. Recent developments greatly enhanced our understanding of role and function in health disease. Pathogenic eosinophilic inflammation can lead to severe diseases various organs, such gastrointestinal tract, airways, heart skin. In a 2-day focus workshop German Society for Allergology Clinical Immunolo...

Background. Eosinophilic esophagitis is an inflammatory condition where there is a dense infiltration of eosinophils typically exceeding fifteen cells per high power field. Familial Mediterranean fever is an autosomal recessive disorder characterized by brief, acute, and self-limited episodes of fever and polyserositis that recur at irregular intervals. Case Presentation. A three-year-and-nine-...

INTRODUCTION Synchronous composite tumors are uncommon. Simultaneous, rather than metachronous or consecutive, occurrences of eosinophilic granuloma and Hodgkin's lymphoma in children are very rare. This is the first report of this kind in the medical literature. CASE PRESENTATION We report the case of a 12-year-old Iranian boy with eosinophilic granuloma localized in his leg around the knee ...

Eosinophilic fasciitis is a rare systemic disease characterized by inflammatory thickening of the skin and underlying fascia, peripheral eosinophilia, elevated inflammatory markers and typical biopsy findings. Internal organ involvement is rare unlike in other fibrosing disorders. Though this is usually a benign disease, it is often difficult to diagnose and the course may also be variable. Glu...

Eosinophilic esophagitis (EE) is a clinical entity characterized by eosinophilic infi ltration limited to the esophageal epithelium without signifi cant eosinophilic infl ammation of the remainder of the upper gastrointestinal tract mucosa. It can occur in isolation or as part of an atopic spectrum together with asthma, allergic rhinitis and/or atopic dermatitis. EE was fi rst described in the ...

The primary study objectives were to estimate the frequencies and rates of gastrointestinal bleeding and peptic ulcerative disorder in HIV-positive patients compared with age- and sex-matched HIV-negative subjects. Data from a US insurance claims database was used for this analysis. Among 89,207 patients with HIV, 9.0% had a GI bleed, 1.0% had an upper gastrointestinal bleed, 5.6% had a lower g...

A 35-year-old lady was admitted to our Department due to fever and symptoms from the respiratory and gastrointestinal system. She was recently diagnosed with eosinophilic gastroenteritis and had been on steroids until two months prior to admission. Legionella pneumophila pneumonia was diagnosed and targeted therapy was initiated. The combined approach to the two entities is discussed as well as...