BACKGROUND Non-eosinophilic asthma is a potentially important clinicopathological phenotype since there is evidence that it responds poorly to inhaled corticosteroid therapy. However, little is known about the underlying airway immunopathology and there are no data from placebo-controlled studies examining the effect of inhaled corticosteroids. METHODS Airway immunopathology was investigated ...

The E2 hypotetraploid Ehrlich ascites tumor reached its peak size at 1 X IO9 cells on the 14th day after i.p. inoculation of 0.30 X 10* cells. During this period the % nonviable Ehrlich ascites tumor cells did not change. Autoradiographic studies during the first 14 days of Ehrlich ascites tumor growth dem onstrated no decrease in the % tumor cells incorporating tritiated uridine, proline, phen...

OBJECTIVE To describe the causes, characteristics and factors associated with ascites in patients on maintenance hemodialysis. STUDY DESIGN Observational study. PLACE AND DURATION OF STUDY Department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation, Karachi, from November 2007 to November 2014. METHODOLOGY All patients on maintenance hemodialysis and age > 16 year...

BACKGROUND The production of ascites is a common complication of ovarian cancer. Ascites constitute a unique tumor microenvironment that may affect disease progression. In this context, we recently showed that ovarian cancer ascites may protect tumor cells from TRAIL-induced apoptosis. In this study, we sought to determine whether the prosurvival effect of ascites affects disease-free intervals...

Myxedema ascites caused by hypothyroidism is rare, so its diagnosis is often delayed and patients frequently receive unnecessary procedures such as liver biopsies and exploratory laparotomies. We report a 71-yr-old man with clinical ascites that was the first manifestation of hypothyroidism, and which resolved completely in response to thyroid hormone replacement therapy. To our knowledge, this...

Ascites can be defined as the abnormal accumulation of fluid inside the peritoneal cavity. Earlier ascites was classified as transudative and exudative based on the total protein concentration of the ascitic fluid. The traditional concept of high protein ascites(> 2.5 g/dl) as exudate was questioned because: (a) the normal peritoneal fluid protein concentration is some times > 4 g/dl(1); (b) th...

abstract background: regarding the diagnostic errors of the classic criteria including serum ascites albumin gradient (saag), total protein concentration and the adapted light et al’s criteria in distinguishing transudate versus exudates, we evaluated the ascitic fluid to serum bilirubin ratio as a new criteria in this regard. we also evaluated whether the combination of bilirubin ratio with ea...

INTRODUCTION Eosinophilic colitis, which is a rare form of eosinophilic gastrointestinal diseases, occurs as primary and secondary allergic eosinophilic colitis of the gastrointestinal tract infection, inflammatory bowel disease, celiac disease, and vasculitis. The diagnosis is based on a significant amount of eosinophils in the inflammatory infiltrate of the colon wall. AIM To analyze the cl...

There are important aspects of the study design that cast doubt on the claim of Cowan et al that ‘modified responses’ to corticosteroids occur in patients with non-eosinophilic asthma. First, the population recruited was more likely to include patients who experienced loss of control of their asthma after steroid withdrawal than those who remained stable or improved. This increases the potentia...

OBJECTIVES Nonasthmatic eosinophilic bronchitis is a newly recognized cause of chronic cough. Our objective was to review the pathogenesis, natural history, diagnosis, and treatment of this condition. METHODS The current literature was reviewed using an Ovid MEDLINE and PubMed literature review for all studies published in the English language from 1963 to December 2004 using the medical subj...