The present study aimed to use RNA interference (RNAi) to silence chemokine receptor 3 (CCR3) and observe the effects on eosinophils (EOS) in mice with allergic rhinitis (AR). CCR3 small interfering RNA (siRNA) lentiviral vectors were transduced into purified EOS cells cultured in vitro. Reverse transcription-polymerase chain reaction (RT-PCR) and western blot analyses were also used to detect ...

PURPOSE UK demographic and legislative changes combined with increasing burdens on National Health Service manpower and budgets have led to extended roles for community optometrists providing locally-commissioned enhanced optometric services (EOS). This realist review's objectives were to develop programme theories that implicitly or explicitly explain quality outcomes for eye care provided by ...

Early onset schizophrenia (EOS) begins in childhood or adolescence. EOS is associated with poor treatment response and may benefit from timely use of clozapine. This study aimed to identify the predictors of clozapine use in EOS and characterize the clinical profile and outcome of clozapine-treated youths with schizophrenia. We conducted a nationwide population-based study using linked data fro...

Background: Pulicaria gnaphalodes, Ducrosia anethifolia, Trachyspermum copticum, Foeniculum vulgare Mill and Majorana hortensis Minch are widely used as herbal plants in traditional medicine and they have been reported to have a variety of therapeutic effects. This study was carried out to evaluate the antimicrobial effects of essential oils (EOs) extracted from these medicinal herbs against si...

Despite the rapid advance of terahertz optoelectronics in the recent decade, the frequency region above 10 THz has yet been accessible for coherent detection. Whereas Katzenllenbogen et al. reported a frequency response of 6 THz from their photoconducting dipole antenna ~PDA!, the record was recently pushed to 7 THz with a much broader 3-dB bandwidth in a GaP-based free-space electro-optic samp...

the present work is the successful extension of an improved equation of state (eos) to refrigerant fluids. the objective is the prediction of isothermal and saturated liquid densities of refrigerants. two temperature-independent parameters appearing in the modified eos are closely related to critical point properties of refrigerant fluids. our results showed that, the proposed eos can predict w...

an analytical equation of state has been previously modified by papari et al. for representing the volumetric properties of molecular fluids. however the performance of that eos has not been yet well investigated for refrigerant fluids. this study extended that equation to 19 liquid refrigerants to predict their densities at isothermal and saturated states. two temperature-independent parameter...

BACKGROUND Even though an inflammatory process is known to be the underlying cause of asthma, diagnosis is based on clinical history, reversible airway obstruction and bronchial hyperresponsiveness according to international guidelines. The fraction of exhaled nitric oxide (FE(NO)) and induced sputum eosinophil count (Eos%) have been used as non-invasive inflammatory biomarkers. OBJECTIVES Th...

The compositions of essential oils (EOs) from Spanish marjoram (Thymus mastichina L.) grown in several bioclimatic zones of Murcia (SE Spain) were studied to determine their absolute and relative concentrations using gas chromatography-mass spectrometry. 1,8-Cineole and linalool were the main components, followed by α-pinene, β-pinene and α-terpineol. (-)-Linalool, (+)-α-terpineol and (+)-α-pin...