Jamshid Pourazar,* Ian S. Mudway,* James M. Samet, Ragnberth Helleday, Anders Blomberg, Susan J. Wilson, Anthony J. Frew, Frank J. Kelly, and Thomas Sandström Department of Respiratory Medicine and Allergy, University Hospital, Umeå, Sweden; Lung Biology, School of Health and Life Sciences, King’s College London, London, United Kingdom; Human Studies Division, National Health and Environmental ...

PURINERGIC RECEPTOR-MEDIATED RAPID DEPLETION OF NUCLEAR pAKT DEPENDS ON PH DOMAIN LEUCINE-RICH REPEAT PHOSPHATASE (PHLPP), CALCINEURIN, PP2A and PTEN PHOSPHATASES Oras Mistafa*, Aram Ghalali*, Sandeep Kadekar, Johan Högberg and Ulla Stenius * contributed equally Institute of Environmental Medicine, Karolinska Institutet, S-171 77 Stockholm, Sweden Running head: pAkt depletion by protein and lip...

1 Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden 2 Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO, USA * Corresponding author: B Fadeel, Division of Molecular Toxicology, Institute of Environmental Medicine, Nobels väg 13, Karolinska Institutet, 171 77 Stockholm, Sweden. Tel: þ 46...

to understand the traditional description of medicine as a practice of healing, it is necessary to examine its relationships with both science and ethics. the “scientific” component of medicine includes an acknowledgment of the influence of social, cultural and environmental factors on the functioning of the organism. the “ethical” component is often presented as merely supplementary but actual...

Jennifer S. Smith*, Urban Kumlin, Fredrik Nyberg, Cristina Fortes, David Zaridze, Wolfgang Ahrens, Irene Bruske-Hohlfeld, Vali Constantinescu, Jie Ting, Simone Benhamou, Lorenzo Simonato, Jens Boman, Valerie Gaborieau and Paolo Boffetta Department of Epidemiology, University of North Carolina, Chapel Hill, NC Department of Virology, University of Umeå, Umeå, Sweden Institute of Environmental Me...

WORKING GROUP David Bernstein (Consultant, Geneva, Switzerland) Vince Castranova (National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA) Ken Donaldson (University of Edinburgh Medical School, Edinburgh, UK) Bice Fubini (Interdepartmental Center “G. Scansetti” for Studies on Asbestos and other Toxic Particulates, University of Torino, Italy) John Hadley (Owens Cor...

Department of Sports Medicine, ASPETAR, Qatar Orthopaedic and Sports Medicine Hospital, Doha, Qatar Institute for Environmental Medicine, Presbyterian Hospital, Dallas, Texas, USA Department of Medicine, University of Texas Southwestern, Dallas, Texas, USA Department of Cardiology, Hartford Hospital, Hartford, Connecticut, USA Department of Medicine, University of Connecticut, Connecticut, USA ...

Kelly J. Brunst, Ph.D.1,2,†, Yuet-Kin Leung, Ph.D.2,3, Patrick H. Ryan, Ph.D.1,2,4, Gurjit K. Khurana Hershey, M.D., Ph.D.5, Linda Levin, Ph.D.1,2, Hong Ji, Ph.D.5, Grace K. LeMasters, Ph.D.1, and Shuk-Mei Ho, Ph.D.2,3,6 1Division of Epidemiology and Biostatistics, University of Cincinnati College of Medicine, 3223 Eden Avenue, Kettering Building, Cincinnati, OH 2Center for Environmental Geneti...

1Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA 52246, USA 2Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA 3Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, Telangana 500037, India 4Center for Precision Environmental Heal...

Manabu Shibasaki, Yasunori Umemoto, Tokio Kinoshita, Ken Kouda, Tomoyuki Ito, Takeshi Nakamura, Craig G. Crandall, and Fumihiro Tajima Department of Health Sciences, Nara Women’s University, Kita-uoya Nishi-machi, Japan; Department of Rehabilitation Medicine, Wakayama Medical University, School of Medicine and Nachi-Katsuura Research Center of Sports Medicine and Balneology, Wakayama-shi, Japan...