In this paper we propose a technique for spectral envelope estimation using maximum values in the sub-bands of Fourier magnitude spectrum (MSASB). Most other methods in the literature parametrize spectral envelope in cepstral domain such as Mel-generalized cepstrum etc. Such cepstral domain representations, although compact, are not readily interpretable. This difficulty is overcome by our meth...

background and aims: infectious bronchitis virus (ibv) is the etiological agent of infectious bronchitis (ib), which is an acute and highly contagious disease of the respiratory and sometimes the urogenital tracts of chickens. in iran, the disease has been identified in chicken flocks with serological and virus isolation methods. gene 3c (e) encode envelop (small membrane) protein. for envelope...

The role of recombination during a common-envelope event has been long debated. Many studies have argued that much hydrogen energy, which is radiated in relatively cool and optically-thin layers, might not thermalise the envelope. On other hand, helium contains 30% total occurs deeper stellar We investigate distinct roles played by interaction experienced 12 solar mass red supergiant donor. per...

Chloroplast precursor proteins encoded in the nucleus depend on their targeting sequences for delivery to chloroplasts. There exist different routes to the chloroplast outer envelope, but a common theme is the involvement of molecular chaperones. Hsp90 (heat-shock protein 90) delivers precursors via its receptor Toc64, which transfers precursors to the core translocase in the outer envelope. In...

The early steps of the hepatitis B virus (HBV) life cycle are still poorly understood. Indeed, neither the virus receptor at the cell surface nor the mechanism by which nucleocapsids are delivered to the cytosol of infected cells has been identified. Extensive mutagenesis studies in pre-S1, pre-S2, and most of the S domain of envelope proteins revealed the presence of two regions essential for ...

BACKGROUND Dengue is a global arboviral threat to humans; causing 390 million infections per year. The availability of safe and effective tetravalent dengue vaccine is a global requirement to prevent epidemics, morbidity, and mortality associated with it. METHODS Five experimental groups (6 mice per group) each of 5-week-old BALB/c mice were immunized with vaccine and placebo (empty plasmid) ...

The surface of the mature dengue virus (DENV) particle is covered with 180 envelope (E) proteins arranged as homodimers that lie relatively flat on the virion surface. Each monomer consists of three domains (ED1, ED2, and ED3), of which ED3 contains the critical neutralization determinant(s). In this study, a large panel of DENV-2 recombinant ED3 mutant proteins was used to physically and biolo...

The Flavivirus genus includes widespread and severe human pathogens like the four serotypes of dengue virus (DENV1 to DENV4), yellow fever virus, Japanese encephalitis virus and West Nile virus. Domain III (ED3) of the viral envelope protein interacts with cell receptors and contains epitopes recognized by virus neutralizing antibodies. Its structural, antigenic and immunogenic properties have ...