نتایج جستجو برای: enrichment analysis

تعداد نتایج: 2852258  

2015
Piyush Bansal Somay Jain Vasudeva Varma

On various microblogging platforms like Twitter, the users post short text messages ranging from news and information to thoughts and daily chatter. These messages often contain keywords called Hashtags, which are semanticosyntactic constructs that enable topical classification of the microblog posts. In this poster, we propose and evaluate a novel method of semantic enrichment of microblogs fo...

2004
Jacob Fish

A new Multiscale Enrichment method based on the Partition of Unity (MEPU) method is presented. It is a synthesis of mathematical homogenization theory and the Partition of Unity method. Its primary objective is to extend the range of applicability of mathematical homogenization theory to problems where scale separation may not be possible. MEPU is perfectly suited for enriching the coarse scale...

Journal: :TACL 2013
Beata Beigman Klebanov Nitin Madnani Jill Burstein

We demonstrate a method of improving a seed sentiment lexicon developed on essay data by using a pivot-based paraphrasing system for lexical expansion coupled with sentiment profile enrichment using crowdsourcing. Profile enrichment alone yields up to 15% improvement in the accuracy of the seed lexicon on 3way sentence-level sentiment polarity classification of essay data. Using lexical expansi...

2005
Alexander Glaser

This paper reviews the rationale of selecting an enrichment of just less than 20% (low-enriched uranium) as the preferred enrichment level for research reactor fuel in order to minimize overall proliferation risks. The net strategic value of the nuclear material associated with reactor operation is evaluated for a variety of enrichment levels, ranging from slightly enriched to weapongrade fuel....

Journal: :Bioinformatics 2009
Adi L. Tarca Sorin Draghici Purvesh Khatri Sonia S. Hassan Pooja Mittal Jung-sun Kim Chong Jai Kim Juan Pedro Kusanovic Roberto Romero

MOTIVATION Gene expression class comparison studies may identify hundreds or thousands of genes as differentially expressed (DE) between sample groups. Gaining biological insight from the result of such experiments can be approached, for instance, by identifying the signaling pathways impacted by the observed changes. Most of the existing pathway analysis methods focus on either the number of D...

Journal: :Bioinformatics 2009
Gabriel F. Berriz John E. Beaver Can Cenik Murat Tasan Frederick P. Roth

UNLABELLED FuncAssociate is a web application that discovers properties enriched in lists of genes or proteins that emerge from large-scale experimentation. Here we describe an updated application with a new interface and several new features. For example, enrichment analysis can now be performed within multiple gene- and protein-naming systems. This feature avoids potentially serious translati...

Journal: :International journal of molecular medicine 2014
Chao Gu Ting Shen

In this study, gene expression profiles in peripheral blood monocytes from patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) were compared with those of healthy individuals to identify key differentially expressed genes (DEGs), in an effort to broaden our understanding of the pathogenesis of these diseases and identify potential therapeutic targets. The microarray data s...

Journal: :Bioinformatics 2012
Anika Groß Michael Hartung Kay Prüfer Janet Kelso Erhard Rahm

MOTIVATION Ontologies are used in the annotation and analysis of biological data. As knowledge accumulates, ontologies and annotation undergo constant modifications to reflect this new knowledge. These modifications may influence the results of statistical applications such as functional enrichment analyses that describe experimental data in terms of ontological groupings. Here, we investigate ...

Journal: :Analytica chimica acta 2014
Chunli Fang Zhichao Xiong Hongqiang Qin Guang Huang Jing Liu Mingliang Ye Shun Feng Hanfa Zou

Selective enrichment of glycopeptides prior to the mass spectrometry (MS) analysis is essential due to ion suppression effect during ionization caused by the co-presence of non-glycosylated peptides. Among the enrichment approaches, hydrophilic interaction liquid chromatography (HILIC) based on magnetic separation has become a popular method in recent years. As the conventional synthesis proced...

Journal: :Methods in molecular biology 2016
Matthias Lienhard Lukas Chavez

DNA enrichment followed by sequencing (DNA-IP seq) is a versatile tool in molecular biology with a wide variety of applications. Computational analysis of differential DNA enrichment between conditions is important for identifying epigenetic alterations in disease compared to healthy controls and for revealing dynamic epigenetic modifications throughout normal and distorted cell differentiation...

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