Traumatic brain injury (TBI) triggers a series of complex pathophysiological processes. These include abnormalities in brain energy metabolism; consequent to reduced tissue pO2 arising from ischemia or abnormal tissue oxygen diffusion, or due to a failure of mitochondrial function. In vivo magnetic resonance spectroscopy (MRS) allows non-invasive interrogation of brain tissue metabolism in pati...

conclusions phoma glomerata pg41 strain sharing natural substrate with toxigenic a. flavus secretes metabolites possessing a significant aflatoxin-degrading activity. the activity is associated mainly with a protein-enriched high-molecular-weight fraction of extracellular metabolites and appears to be of enzymatic origin. results the afb1-degrading activity of protein-enriched fractions, isolat...

In this study, the effect of 14 years GE exclusion in a desert grassland on soil microbial community diversity and metabolites was examined. changed bacterial structure, alpha community, total phosphorus (TP) potassium (TK) content soil. More specifically, relative abundance Actinobacteria, Proteobacteria, Chloroflexi increased with GE. contrast, Acidobacteria higher during grazing (G), so it i...

The heart is the largest consumer of energy per gram of tissue, and disruptions in energy metabolism, including energy supply and demand, are thought to play a central role in many common diseases affecting the heart. Therefore, it is perhaps inevitable that the first human cardiac spectroscopy focused on those energy metabolites that are NMR-detectable.1,2 Phosphorus (31P) NMR spectroscopy (MR...

BACKGROUND AND PURPOSE Treatment with the ketone body precursor 1,3-butanediol has been suggested to ameliorate hypoxic/ischemic brain damage. Butanediol could provide an alternative energy substrate for the brain, thereby decreasing the amount of glycolytically produced lactate. Hyperglycemia aggravates brain damage after brain ischemia and causes fatal postischemic seizures, probably by incre...

BACKGROUND The design of photobioreactor (PBR) for outdoor mass cultivation of microalgae determines the distribution of solar irradiance among cells in the culture, mode of agitation, mass transfer efficacy, and energy consumption, thus determines the productivity of the system and the cost of production. In this study, the concept of a floating photobioreactor with rotation function is propos...

BACKGROUND A reliable quenching and metabolite extraction method has been developed for Lactobacillus plantarum. The energy charge value was used as a critical indicator for fixation of metabolism. RESULTS Four different aqueous quenching solutions, all containing 60% of methanol, were compared for their efficiency. Only the solutions containing either 70 mM HEPES or 0.85% (w/v) ammonium carb...

The following studies were carried out to examine energy metabolites and cardiac performance of the failing heart (hereditary cardiomyopathy) of the Syrian hamster (strain UM-X7.1) perfused either by normal or stress conditions, and to determine whether cyclical changes in energy-related metabolites occurred in the glucose-perfused hearts of both normal and heart failure animals. Hamster hearts...

BACKGROUND Total fat and omega-3 fatty acids in the diet may affect breast cancer risk by altering estrogen metabolism. The purpose of this study was to elucidate the effects of differing total fat and omega-3 fatty acid content of diets on a panel of urinary estrogens and metabolites. FINDINGS A controlled, cross-over feeding trial was conducted in postmenopausal women using three test diets...

Energy metabolism is a very important process to improve and maintain health from the point of view of physiology. It is well known that the intracellular ATP production is contributed to energy metabolism in cells. Cistus monspeliensis is widely used as tea, spices, and medical herb; however, it has not been focusing on the activation of energy metabolism. In this study, C. monspeliensis was i...