Deamidated gliadin peptide antibodies have recently been suggested as reliable tools for celiac disease (CD) diagnosis. We compared their utility for diagnosis CD in comparison to the routinely used anti-endomysial, and anti-tissue transglutaminase antibodies. We studied 65 patients (17 men, 48 women; age range, 17- 63 years) who underwent intestinal biopsy because of clinical suspicion of smal...

AIM To re-evaluate all patients diagnosed histologically as having peptic duodenitis who had known endomysial antibody (EMA) test results to find out whether they would still be classified as peptic duodenitis on histological analysis and to review their subsequent clinical course. METHODS All mucosal biopsy specimens of the second part of the duodenum which were reported as showing features ...

OBJECTIVE To provide clinicians with an update on the diagnosis of celiac disease (CD) and to make recommendations on the indications to screen for CD in patients presenting with low bone mineral density (BMD) or fragility fractures. QUALITY OF EVIDENCE A multidisciplinary task force developed clinically relevant questions related to the diagnosis of CD as the basis for a literature search of...

This is often a frustratingly non-specific reason for referral to gastrointestinal clinics for investigation. For a few patients, serology with gliadin antibodies supported by endomysial antibody tests positive will lead to small bowel biopsy and the diagnosis of coeliac disease. However, for the majority where menorrhagia and epistaxis have been excluded, invasive tests are needed as a primary...

Background: Decay of vaccine–induced antibody titres without boosting of the wild measles virus has been well documented. Revaccination against measles has reduced the prevalence of the disease worldwide. Revaccination may cause IgE induced anaphylaxis. Objective: To study measles IgG antibody in revaccinated populations and its relation to IgE induced hypersensitivity. Methods: Blood samples w...

BACKGROUND Various ultrasonographic (US) signs have been reported in overt celiac disease (CD). The aim of this study was to investigate the diagnostic accuracy of 6 US parameters in predicting CD. METHODS One hundred sixty-two consecutive patients with chronic diarrhea (n=105), iron deficiency anemia (n=25), or dyspepsia (n=32) underwent anti-endomysial IgA antibody determination and duodena...

Background: Inhibitory antibody to exogenous Factor VIII (FVIII) is a major complication of hemophilia treatment. This study was conducted to determine the prevalence of inhibitor antibody directed against FVIII.Methods: From May 2010 to May 2011, 52 patients with severe hemophilia A admitted in Amirkola Children’s Hospital were evaluated. Those who had abnormal mixing study, antibody against F...

objective: seeking for fertility after previous vasectomy is increasing. vasectomy may break the blood testis barrier and in this way the level of antisperm antibody increases. it is suggested that increase in antisperm antibody decreases spontaneous pregnancy even after successful vasovasostomy. in this study we evaluated antisperm antibody formation 3 months after vasectomy. method: this stud...

conclusions in this city, a great proportion of children are susceptible to hepatitis a and it’s complications at an older age. this decrease in seropositivity may be caused by elevated hygien level. according to our results hepatitis a vaccination is recommended at early childhood such as that of other regions where low prevalence of hepatitis a infection is found. patients and methods this cr...