Partial sequencing of the 16S-23S rDNA intergenic spacer showed two to four genotypes each for Borrelia hermsii and B. turicatae, both relapsing fever agents transmitted by argasid ticks, and for B. miyamotoi and B. lonestari, transmitted by ixodid ticks. Field surveys of Ixodes ticks in Connecticut and Sweden showed limited local diversity for B. miyamotoi.

Immunological cross-reactivity has been shown between related genera of the family Treponemataceae. Extracts of Borrelia cross-react with antibodies in syphilitic serum (Saurino and De Lamater, 1952) and produce positive skin tests in the later stages of syphilis (Ranque, Quilici, and Assadourian, 1967). The fluorescent treponemal antibody absorption test (FTA-ABS) is at present considered to b...

Railivay Hospital, Hubli, M. and S. M. Railway. Th? following cases of relapsing fever were admitted to this hospital during a local epidemic in August to October 1923. Some of them might have been mistaken for plague, had not the diagnosis been confirmed in each instance by the finding of spirochetes in blood films:? Case 1, aet. 27.?Admitted to hospital for continuous fever for 6 days, slight...

Previous studies revealed that the heart suffers significant injury during experimental Lyme and relapsing fever borreliosis when the immune response is impaired (D. Cadavid, Y. Bai, E. Hodzic, K. Narayan, S. W. Barthold, and A. R. Pachner, Lab. Investig. 84:1439-1450, 2004; D. Cadavid, T. O'Neill, H. Schaefer, and A. R. Pachner, Lab. Investig. 80:1043-1054, 2000; and D. Cadavid, D. D. Thomas, ...

BACKGROUND In the United States, Tick-Borne Relapsing Fever (TBRF) in dogs is caused by the spirochete bacteria Borrelia turicatae and Borrelia hermsii, transmitted by Ornithodoros spp. ticks. The hallmark diagnostic feature of this infection is the visualization of numerous spirochetes during standard blood smear examination. Although the course of spirochetemia has not been fully characterize...

We conducted repeat muscle MR imaging (figure) on a 46-yearold man with relapsing eosinophilic fasciitis that can be classified in a continuum around the so-called Shulman syndrome.1 The patient had a 6-month history of relapsing fever and pain and swelling of the lower limbs, which responded to a moderate dosage of corticosteroids but relapsed several times after tapering of corticosteroids. I...

Relapsing fever borreliae require lipid compounds for growth in vitro. In this study, the major pathways of lipid catabolism in three species of tick-borne relapsing fever borreliae were investigated. Thin-layer chromatography was used to compare chloroform-methanol extracts of fresh culture media with extracts of exhausted culture media after organisms were removed by centrifugation. The chrom...

under twelve were eleven, five girls and six boys. The youngest patient was a female child eleven months old. All the cases occurred in lower class patients. They were poor in circumstances and sanitation. Eleven were members of the same family ; all of them recovered. The first case was detected by microscopical examination of the blood of a female child ten years old who was brought to the di...

Phylogenetic analysis based on A) the 16S ribosomal RNA gene (16SrRNA) and B) flagellin gene of Borrelia spp. Representative Borrelia spp. were used. GenBank accession numbers are in parentheses. For the amplification and direct sequencing of 16SrRNA, the 4 PCR primers rrs-F1 (5′-ATAACGAAGAGTTTGATCCTGGCT-3′), rrs-F2 (5′-GGTGTAAGGGTGGAATCTGTTG-3′), rrs-R3 (5′-TTTCGTGACTCAGCGTCAGT-3′), and rrs-R4...

In July 2013, a resident of the Bitterroot Valley in western Montana, USA, contracted tickborne relapsing fever caused by an infection with the spirochete Borrelia hermsii. The patient's travel history and activities before onset of illness indicated a possible exposure on his residential property on the eastern side of the valley. An onsite investigation of the potential exposure site found th...