We present an infant with true trisomy 22. Mosaicism is ruled out by the finding of a 47,XX, +22 karyotype in all cells analysed originating from two embryonic germ layers. The physical findings are consistent with the previously noted features including developmental delay, ear abnormalities, micrognathia, clefting, and congenital heart disease. The patient is the first described with macrocep...

while our knowledge of anuran embryonic and larval surface ciliation and their diversity ofciliation patterns are significant, very few references were noticed on embryonic ciliation in direct-developinganurans, such as species in the genus eleutherodactylus. eleutherodactylus urichi embryos were found tohave surface ciliated cells during much of their development until a few days before hatchi...

In many arthropods, the appearance of new segments and their differentiation are not completed by end embryogenesis but continue, in different form degree, well after hatching, some cases up to last post-embryonic molt. Focusing on segmentation process currently described as segment addition (or, anamorphosis), we revise here current knowledge discuss it an evolutionary framework which involves...

BACKGROUND IVF occasionally produces aneuploid zygotes with one or three pronuclei (PN). Routinely, these zygotes are discarded. The aim of this work was to establish human embryonic stem cell (hESC) lines from blastocysts resulting from abnormal fertilization. METHODS Abnormally fertilized zygotes were cultured to the blastocyst stage and, following zona pellucida digestion, zona-free blasto...

Neurotrophin-3 and its receptor TrkC are expressed during the development of the mammalian cerebral cortex. To examine whether neurotrophin-3 might play a role in the elaboration of layer-specific cortical circuits, slices of layer 6 and layers 2/3 neurons were cultured in the presence of exogenously applied neurotrophin-3. Results indicate that neurotrophin-3 promotes axonal branching of layer...

A germ layer is a group of cells in an embryo that interact with each other as the embryo develops and contribute to the formation of all organs and tissues. All animals, except perhaps sponges, form two or three germ layers [6]. The germ layers [6] develop early in embryonic life, through the process of gastrulation [7]. During gastrulation [7], a hollow cluster of cells called a blastula [8] ...

A germ layer is a group of cells in an embryo that interact with each other as the embryo develops and contribute to the formation of all organs and tissues. All animals, except perhaps sponges, form two or three germ layers [6]. The germ layers [6] develop early in embryonic life, through the process of gastrulation [7]. During gastrulation [7], a hollow cluster of cells called a blastula [8] ...

The fate of cells in the epiblast at prestreak and early primitive streak stages has been studied by injecting horseradish peroxidase (HRP) into single cells in situ of 6.7-day mouse embryos and identifying the labelled descendants at midstreak to neural plate stages after one day of culture. Ectoderm was composed of descendants of epiblast progenitors that had been located in the embryonic axi...

BACKGROUND Alzheimer's disease (AD) is the most common form of dementia and the number of AD patients continues to increase worldwide. Components of the germ layer and bran of Brown rice (BR) help maintain good health and prevent AD. Because the germ layer and bran absorb little water and are very hard and difficult to cook, they are often removed during processing. To solve these problems, in ...