Mutations identified in a cohort of patients with atrioventricular septal defects as a part of Ellis van Creveld syndrome (EvC syndrome) led us to study the role of two non-homologous genes, EVC and LBN, in heart development and disease pathogenesis. To address the cause of locus heterogeneity resulting in an indistinguishable heart-hand phenotype, we carried out in situ hybridization and immun...

The Crystallographic data of the α-DIPAB sample was measured using powder X-ray diffraction (PXRD). The crystal structure was also optimized using density functional based method. The calculations were performed both including van der Waals (vdW) interactions and excluding them to quantify the effects of vdW interaction on the crystal formation. The vibrational modes of DIPAB crystal correspond...

The official 2006 kernel workshop " 10 years of kernel machines " Koninklijke Vlaamse Academie van België Sponsors De Wetenschappelijke Onderzoeksgemeenschap (WOG) " Machine Learning for Data Mining and its Applications " De Koninklijke Vlaamse Academie van Belgie (KVAB) The PASCAL network of excellence

The recent experimental results on deep inelastic polarized lepton scattering off proton, deuteron and He together with polarized neutron β-decay data are analyzed. It is shown that the problem of Ellis-Jaffe and Bjorken sum rules deficiency and the neutron paradox could be solved simultaneously by assuming the small right handed current (RHC) admixture in the weak interaction Lagrangian. The p...

During a study of the helminth fauna of 1,643 rodents trapped along the Mekong River (Thailand, Lao People's Democratic Republic and Cambodia) in 2008-2011, the spirurid nematode Physaloptera ngoci Le-Van-Hoa, 1961 was recovered with an overall prevalence of 2.8%. Based on the original description, it was identified in nine of 23 different Murinae host species and is here reported for the first...

Bunmi S. Malau-Aduli, Sue Mulcahy, Emma Warnecke, Petr Otahal, Peta-Ann Teague, Richard Turner, Cees Van der Vleuten School of Medicine, Faculty of Health Science, University of Tasmania, Hobart, Australia Centre for the Advancement of Learning and Teaching, University of Tasmania, Hobart, Australia Menzies Research Institute, Hobart, Australia School of Medicine and Dentistry, Faculty of Medic...

Miranda Olff*, Mirjam Van Zuiden, Saskia B. J. Koch, Laura Nawijn, Jessie L. Frijling and Dick J. Veltman Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Arq Psychotrauma Expert Group, Diemen, The Netherlands; Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands *Correspondence to: Miranda Olff, Email: m.olff@...

The fundamental understanding of molecule-surface reactions is of great importance to heterogeneous catalysis, motivating many theoretical and experimental studies. Even though much attention has been dedicated to the dissociative chemisorption of N2 on tungsten surfaces, none of the existing theoretical models has been able to quantitatively reproduce experimental reaction probabilities for th...

Maximum Likelihood (ML) optimization schemes are widely used for parameter inference. They maximize the likelihood of some experimentally observed data, with respect to the model parameters iteratively, following the gradient of the logarithm of the likelihood. Here, we employ a ML inference scheme to infer a generalizable, physics-based coarse-grained protein model (which includes Go̅-like bias...

We perform large-scale quasi-continuum simulations to determine the stable cross-sectional configurations of free-standing multi-walled carbon nanotubes (MWCNTs). We show that at an inter-wall spacing larger than the equilibrium distance set by the inter-wall van der Waals (vdW) interactions, the initial circular cross-sections of the MWCNTs are transformed into symmetric polygonal shapes or as...