Distributed computing has become a complex ecosystem of protocols and services for managing computation and data. Distributed applications are becoming complex as well. Users, particularly in scientific fields, wish to deploy large numbers of applications with complex dependencies and a large appetite for both computation and data. How may such systems and applications be brought together? I pr...

Benzyl bromides and related molecules are among the most common substrates in organic synthesis. They are typically used as electrophiles in nucleophilic substitution reactions. These molecules can also be activated via single-electron-transfer (SET) process for radical reactions. Representative recent progress includes α-carbon benzylation of ketones and aldehydes via photoredox catalysis. Her...

Conventional Suzuki–Miyaura arylations use halogenated compounds as electrophilic coupling partners. Although the catalytic activation of organohalides is well established, these substrates are seldom naturally abundant and questions exist to their metabolic environmental friendliness. Owing existence readily available chemical feedstocks, alcohols highly desirable cross-coupling partners, alth...

A simple and sensitive kinetic method is described for the determination of ketoprofen in pure form, pharmaceuticals and biological fluids. The method utilizes an oxidative- coupling reaction based upon oxidation of 3-methyl-2-benzo-thiazolinone hydrazone hydrochloride (MBTH) with Ce(IV) in presence of HCl, where an electrophilic intermediate (diazonium salt of the reagent) is produced, then co...

Intramolecular nucleophilic and electrophilic cyclization of N-alkyne-substituted pyrrole esters is described. Efficient routes towards the synthesis of pyrrolopyrazinone, pyrrolotriazinone and pyrrolooxazinone have been developed. First, N-alkyne-substituted pyrrole ester derivatives were synthesized. Introduction of various substituents into the alkyne functionality was accomplished by a copp...

Silane coupling agent generally use as improve the properties of white filler use in rubber compound for better dispersion. Also silane coupling agent reacts with organic filler & polymer chain as crosslink. Here in this research study the crosslink density & swelling phenomena of silane participate in vulcanization process with Nitrile rubber compound. Also show the comparisons of carbon fille...

The problem of self-tuning of coupling parameters in multi-agent systems is considered. Agent dynamics are described by a discrete-time double integrator with unknown input gain. Each agent locally tunes the strength of interaction with neighboring agents by using a normalized gradient algorithm (NGA). The tuning algorithm minimizes the square of the error between an individual agent’s state (v...

Protonation of the highly reactive 1:l intermediate produced in the reaction between triphenylphosphine and dimethyl acetylenedicarboxylate by 2- hydroxyacetophenone leads to vinyltriphenylphosphonium salt, which undergoes aromatic electrophilic substitution reaction with the conjugate base to produce compounds 4,5, and 6 in 1 : 1.2:0.5 ratios